Fenazaquin

Structural formula
General
Surname	Fenazaquin
other names	4- {2- [4- (1,1-dimethylethyl) phenyl] ethoxy} quinazoline
Molecular formula	C 20 H 22 N 2 O
Brief description	colorless solid
External identifiers / databases
EC number	410-580-0
ECHA InfoCard	100.101.016
PubChem	86356
ChemSpider	77874
Wikidata	Q1404580
properties
Molar mass	306.41 g mol −1
Physical state	firmly
Melting point	78.5 ° C
solubility	almost insoluble in water; soluble in many organic solvents;
safety instructions
H and P phrases	H: 301-332-410
	P: 273-301 + 310-501
Toxicological data	136 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Fenazaquin is a chemical compound from the group of quinazoline derivatives and alkyl aryl ethers .

Extraction and presentation

Fenazaquin can be obtained by reacting 4-quinazolinol with triphenyl phosphite and chlorine and then reacting the intermediate product 4-chloroquinazoline with 4- tert- butylphenylethanol .

properties

Fenazaquin is a colorless solid that is insoluble in water. It hydrolyzes under acidic conditions, but is almost stable under neutral or basic conditions.

use

Fenazaquin has been used as an acaricide since it was first introduced in 1992 . It works by blocking the mitochondrial electron transport in complex I.

Admission status

Fenazaquin is approved as an active ingredient in the EU countries, but pesticides that contain fenazaquin as an active ingredient are not commercially available in Germany, Austria or Switzerland.

Individual evidence

↑ ^a ^b ^c ^d ^e Entry on 4- (2- (4- (1,1-Dimethylethyl) phenyl) ethoxy) quinazoline in the GESTIS substance database of the IFA , accessed on February 6, 2017(JavaScript required) .
↑ ^a ^b ^c ^d Ullmann's Agrochemicals, Volume 1 . Wiley-VCH, 2007, ISBN 978-3-527-31604-5 ( page 558 in the Google book search).
↑ Entry on Fenazaquin (ISO) in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on March 15, 2017. Manufacturers or distributors can expand the harmonized classification and labeling .
^ Terence Robert Roberts, DH Hutson: Metabolic pathways of agrochemicals . Royal Soc of Chemistry, 1999, ISBN 978-0-85404-499-3 ( page 224 in Google book search).
^ Horst Börner: Plant diseases and plant protection . Springer, 2009, ISBN 978-3-540-49067-8 ( page 588 in the Google book search).
↑ Directorate-General for Health and Food Safety of the European Commission: Entry on fenazaquin in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on December 6, 2019.

[GESTIS-1] Entry on 4- (2- (4- (1,1-Dimethylethyl) phenyl) ethoxy) quinazoline in the GESTIS substance database of the IFA , accessed on February 6, 2017(JavaScript required) .

[ullmann-2] Ullmann's Agrochemicals, Volume 1 . Wiley-VCH, 2007, ISBN 978-3-527-31604-5 ( page 558 in the Google book search).

[CLP_100.101.016-3] Entry on Fenazaquin (ISO) in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on March 15, 2017. Manufacturers or distributors can expand the harmonized classification and labeling .

[mpw-4] Terence Robert Roberts, DH Hutson: Metabolic pathways of agrochemicals . Royal Soc of Chemistry, 1999, ISBN 978-0-85404-499-3 ( page 224 in Google book search).

[Pflanzenschutz-5] Horst Börner: Plant diseases and plant protection . Springer, 2009, ISBN 978-3-540-49067-8 ( page 588 in the Google book search).

[PSM-6] Directorate-General for Health and Food Safety of the European Commission: Entry on fenazaquin in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on December 6, 2019.