Flonicamid

Structural formula
General
Surname	Flonicamid
other names	N - (cyanomethyl) -4- (trifluoromethyl) nicotinamide; N -cyanomethyl-4-trifluoromethyl-3-pyridinecarboxamide;
Molecular formula	C 9 H 6 F 3 N 3 O
Brief description	creamy white or light beige, odorless powder
External identifiers / databases
EC number	605-127-0
ECHA InfoCard	100.119.736
PubChem	9834513
Wikidata	Q4328316
properties
Molar mass	229.16 g mol −1
Physical state	firmly
density	1.53 g cm −3
Melting point	157.5 ° C
boiling point	decomposes at 306-320 ° C
Vapor pressure	0.00255 mPa (25 ° C)
solubility	practically insoluble in water (5.2 mg l −1 at 20 ° C); easily soluble in acetone;
safety instructions
GHS hazard labeling from Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary Caution
H and P phrases	H: 302
	P: no P-phrases
Toxicological data	884 mg kg −1 ( LD 50 , rat , oral ) ; > 5000 mg kg −1 ( LD 50 , rabbit , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Flonicamid is a chemical compound from the group of pyridine carboxamides and is used as an insecticide under the trade name Teppeki . Flonicamid acts selectively against uniforms and is used against aphids . The exact mechanism of action is not known.

Extraction and presentation

Flonicamid can be prepared by reacting trifluoromethylpyridinecarboxylic acid with thionyl chloride and aminoacetonitrile .

Admission

In the European Union, Flonicamid was approved for use as an insecticide with effect from September 1, 2010. Flonicamid is contained in approved plant protection products in Germany, Austria and Switzerland.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g PSM approval report Flonicamid
↑ ^a ^b Data sheet Flonicamid, PESTANAL at Sigma-Aldrich , accessed on May 19, 2017 ( PDF ).
↑ Entry on Flonicamid in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ ^a ^b Official data sheet (PDF; 623 kB)
↑ Wolfgang Krämer, Ulrich Schirmer, Peter Jeschke, Matthias Witschel: Modern Crop Protection Compounds: Herbicides, Volume 1 . Wiley-VCH, Weinheim 2011, ISBN 978-3-527-32965-6 , pp. 1231 ( limited preview in Google Book search).
↑ Directive 2010/29 / EU of the Commission of April 27, 2010 (PDF) amending Council Directive 91/414 / EEC to include the active ingredient flonicamid (IKI-220).
↑ General Directorate Health and Food Safety of the European Commission: Entry on Flonicamid (IKI-220) in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; Retrieved February 19, 2016.

[bvl-1] ↑ ^a ^b ^c ^d ^e ^f ^g PSM approval report Flonicamid

[Sigma-2] Data sheet Flonicamid, PESTANAL at Sigma-Aldrich , accessed on May 19, 2017 ( PDF ).

[CLP_100.119.736-3] Entry on Flonicamid in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[isk-4] Official data sheet (PDF; 623 kB)

[mcp1-5] Wolfgang Krämer, Ulrich Schirmer, Peter Jeschke, Matthias Witschel: Modern Crop Protection Compounds: Herbicides, Volume 1 . Wiley-VCH, Weinheim 2011, ISBN 978-3-527-32965-6 , pp. 1231 ( limited preview in Google Book search).

[6] Directive 2010/29 / EU of the Commission of April 27, 2010 (PDF) amending Council Directive 91/414 / EEC to include the active ingredient flonicamid (IKI-220).

[7] General Directorate Health and Food Safety of the European Commission: Entry on Flonicamid (IKI-220) in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; Retrieved February 19, 2016.