Fluopicolide

Structural formula
General
Surname	Fluopicolide
other names	2,6-dichloro- N - [3-chloro-5-trifluoromethyl-2-pyridylmethyl] benzamide
Molecular formula	C 14 H 8 Cl 3 F 3 N 2 O
Brief description	odorless, beige-colored solid
External identifiers / databases
EC number	607-285-6
ECHA InfoCard	100.110.208
PubChem	11159021
Wikidata	Q13636695
properties
Molar mass	383.58 g mol −1
Physical state	firmly
Melting point	150 ° C
solubility	practically insoluble in water (2.8 mg l −1 at 20 ° C); easily soluble in DMSO (183 g l −1 at 20 ° C);
safety instructions
GHS labeling of hazardous substances Caution
H and P phrases	H: 400
	P: 273
Toxicological data	> 5000 mg kg −1 ( LD 50 , rat , oral ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Fluopicolide is a chemical compound from the group of benzamides , or more precisely the acylpicolide. The compound was developed by Bayer CropScience and launched as a fungicide in 2006 .

use

As a fungicide, fluopicolide is particularly effective against egg fungi ( Oomycetes ) such as Phytophthora infestans , Plasmopara viticola , Pythium , Bremia lactucae and Pseudoperonospora cubensis . It is used in numerous agricultural crops.

It is the only representative of the new class of active ingredients, the spectrin- delocalizing fungicides.

Admission

In Germany, Austria and Switzerland, plant protection products containing fluopicolide are approved. Fluopicolide is offered either with fosetyl aluminum for viticulture or with propamocarb for growing potatoes and vegetables.

Individual evidence

↑ ^a ^b ^c ^d Entry on fluopicolide. In: Römpp Online . Georg Thieme Verlag, accessed on July 23, 2014.
↑ ^a ^b ^c Fluopicolide, a new Anti-oomycetes Fungicide with a New Mode of Action inducing Perturbation of a Spectrin-like Protein ( doi : 10.1002 / 9783527619580.ch19 ) In: Wolfgang Krämer, Ulrich Schirmer, Peter Jeschke, Matthias Witschel: Modern Crop Protection Compounds: Herbicides, Volume 1 . Wiley-VCH, 2011, ISBN 978-3-527-32965-6 , pp. 831 ( limited preview in Google Book search).
↑ ^a ^b Fluopicolide data sheet from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

↑ Directorate-General for Health and Food Safety of the European Commission: Entry on fluopicolide in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 14, 2016.

[roempp-1] Entry on fluopicolide. In: Römpp Online . Georg Thieme Verlag, accessed on July 23, 2014.

[mcp-2] Fluopicolide, a new Anti-oomycetes Fungicide with a New Mode of Action inducing Perturbation of a Spectrin-like Protein ( doi : 10.1002 / 9783527619580.ch19 ) In: Wolfgang Krämer, Ulrich Schirmer, Peter Jeschke, Matthias Witschel: Modern Crop Protection Compounds: Herbicides, Volume 1 . Wiley-VCH, 2011, ISBN 978-3-527-32965-6 , pp. 831 ( limited preview in Google Book search).

[Sigma-3] Fluopicolide data sheet from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

[PSM-4] Directorate-General for Health and Food Safety of the European Commission: Entry on fluopicolide in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 14, 2016.