Formothion

Structural formula
General
Surname	Formothion
other names	S - [2- (Formylmethylamino) -2-oxoethyl] - O , O -dimethyldithiophosphate; O, O -Dimethyl- S - (3-methyl-2,4-dioxo-3-azabutyl) dithiophosphate; Anthio; Aflix;
Molecular formula	C 6 H 12 NO 4 PS 2
External identifiers / databases
EC number	219-818-6
ECHA InfoCard	100.018.017
PubChem	17345
Wikidata	Q5470249
properties
Molar mass	257.27 g mol −1
Physical state	firmly
density	1.361 g cm −3
Melting point	25-26 ° C
solubility	hardly soluble in water (2.6 g l −1 )
safety instructions
GHS hazard labeling from Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary Caution
H and P phrases	H: 312-302
	P: 210-260-280-301 + 310-305 + 351 + 338-370 + 378
Toxicological data	250 mg kg −1 ( LD 50 , rat , oral ) ; 350 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Formothione is a chemical compound from the group of thiophosphoric acid esters . Formothion is used as an insecticide and was approved in Germany from 1971 to 1974.

The use of the active ingredient formothion in plant protection products is not permitted in the European Union. In Germany, Austria and Switzerland, no pesticides are currently approved that contain formothione as an active ingredient.

Extraction and presentation

Formothione can be obtained by reacting chloroacetic acid chloride and N -methylformamide with O , O -dimethyldithiophosphoric acid (DMPA) and ammonium hydroxide.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f Entry on formothion in the GESTIS substance database of the IFA , accessed on October 27, 2013(JavaScript required) .
↑ Entry on Formothion in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Formothion solution data sheet , ~ 80% in xylene from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).
↑ Regulation (EC) No. 2076/2002 of the Commission of November 20, 2002 (PDF) extending the deadline according to Article 8 (2) of Council Directive 91/414 / EEC and on the non-inclusion of certain active substances in Annex I of this Directive and the revocation of the approval of plant protection products with these active substances.
^ Directorate-General for Health and Food Safety of the European Commission: Entry on Formothion in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 18, 2016.

↑ Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 355 ( limited preview in Google Book Search).

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f Entry on formothion in the GESTIS substance database of the IFA , accessed on October 27, 2013(JavaScript required) .

[CLP_100.018.017-2] Entry on Formothion in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[Sigma-3] Formothion solution data sheet , ~ 80% in xylene from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

[4] Regulation (EC) No. 2076/2002 of the Commission of November 20, 2002 (PDF) extending the deadline according to Article 8 (2) of Council Directive 91/414 / EEC and on the non-inclusion of certain active substances in Annex I of this Directive and the revocation of the approval of plant protection products with these active substances.

[PSM-5] Directorate-General for Health and Food Safety of the European Commission: Entry on Formothion in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 18, 2016.

[unger-6] Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 355 ( limited preview in Google Book Search).