Heartland Virus
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| Heartland banyang virus | ||||||||||||||||||||||
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The Heartland virus (HRTV) is an enveloped RNA virus , of the proposed species Heartland banyangvirus . Together with the species Huaiyangshan banyangvirus (SFTS virus, Bhanja virus) it is placed in the newly established genus Banyangvirus of the family Pehuiviridae from the order Bunyavirales . According to a previous alternative proposal, the Heartland virus is located together with the SFTS virus in a common species ' Tick-borne phlebovirus ' in the genus Phlebovirus of the same family Phenuiviridae .
Heartland virus is a tick- borne arbovirus .
properties
Heartland virus was first discovered and described in northwest Missouri by Scott Folk at the Heartland Regional Medical Center in St. Joseph, Missouri. The symptoms observed in two farmers in June 2009 were fever , fatigue , diarrhea and a lack of white blood cells ( leukopenia ) and platelets ( thrombopenia ). First, Ehrlichia chaffeensis suspected as a symptom polluters, treatment with doxycycline but not struck and Ehrlichia could not be detected. The search for a virus was then successful.
A study by the CDC of 56,000 ticks collected on site found 10 copies of the virus. The Chinese discovered SFTS virus (SFTS for English severe fever with thrombocytopenia syndrome ) from the same family Phenuiviridae in the order of the Bunya causes a similar disease.
Web links
- n-tv.de: Bite with consequences: ticks transmit new pathogens . Retrieved July 23, 2013.
- NY Times: New Virus Tied to Ticks Poses Puzzle for Doctors. . Retrieved July 23, 2013.
- ICTV Virus Taxonomy, 2016 release. Order: Bunyavirales
Individual evidence
- ↑ ICTV Master Species List 2018b v1 MSL # 34, Feb. 2019
- ↑ a b ICTV: ICTV Taxonomy history: Akabane orthobunyavirus , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)
- ↑ Piet Maes et al. : Expansion of the order Bunyavirales , ICTV Technical Report, June 2018, doi: 10.13140 / RG.2.2.25861.40163
- ↑ Shu Shen, Xiaomei Duan, Bo Wang, Liying Zhu, Yanfang Zhang, Jingyuan Zhang, Jun Wang, Tao Luo, Chun Kou, Dan Liu, Chuanwei Lv, Lei Zhang, Chenchen Chang, Zhengyuan Su, Shuang Tang, Jie Qiao, Abulimiti Moming, Cheng Wang, Abulikemu Abudurexiti, Hualin Wang, Zhihong Hu, Yujiang Zhang, Surong Sun, Fei Deng: A novel tick-borne phlebovirus, closely related to severe fever with thrombocytopenia syndrome virus and Heartland virus, is a potential pathogen , in: Nature: Emerging Microbes & Infections, Volume 7, Article No. 95, May 25, 2018, doi : 10.1038 / s41426-018-0093-2
- ↑ Laura K. McMullan, Scott M. Folk, Aubree J. Kelly, Adam MacNeil, Cynthia S. Goldsmith, Maureen G. Metcalfe, Brigid C. Batten, César G. Albariño, Sherif R. Zaki, Pierre E. Rollin, William L. Nicholson, and Stuart T. Nichol: A New Phlebovirus Associated with Severe Febrile Illness in Missouri . In: New England Journal of Medicine . 367, August 30, 2012, pp. 834-841. Retrieved July 23, 2013.
- ↑ Harry M. Savage, Marvin S. Godsey Jr., Amy Lambert, Nickolas A. Panella, Kristen L. Burkhalter, Jessica R. Harmon, R. Ryan Lash, David C. Ashley, William L. Nicholson: First Detection of Heartland Virus (Bunyaviridae: Phlebovirus) from Field Collected Arthropods In: Am J Trop Med Hyg. (2013), doi : 10.4269 / ajtmh.13-0209 . Retrieved July 23, 2013.
- ↑ Xue-Jie Yu, Mi-Fang Liang, Shou-Yin Zhang, Yan Liu, Jian-Dong Li, Yu-Lan Sun, Lihong Zhang, Quan-Fu Zhang, Vsevolod L. Popov, Chuan Li, Jing Qu, Qun Li , Yan-Ping Zhang, Rong Hai, Wei Wu, Qin Wang, Fa-Xian Zhan, Xian-Jun Wang, Biao Kan, Shi-Wen Wang, Kang-Lin Wan, Huai-Qi Jing, Jin-Xin Lu, Wen- Wu Yin, Hang Zhou, Xu-Hua Guan, Jia-Fa Liu, Zhen-Qiang Bi, Guo-Hua Liu, Jun Ren, Hua Wang, Zhuo Zhao, Jing-Dong Song, Jin-Rong He, Tao Wan, Jing- Shan Zhang, Xiu-Ping Fu, Li-Na Sun, Xiao-Ping Dong, Zi-Jian Feng, Wei-Zhong Yang, Tao Hong, Yu Zhang, David H. Walker, Yu Wang, De-Xin Li: Fever with Thrombocytopenia Associated with a Novel Bunyavirus in China , In: New England Journal of Medicine (2011), Volume 364, pp. 1523-1532. doi : 10.1056 / NEJMoa1010095 . Retrieved July 23, 2013.
