Joan Brugge

Joan Siefert Brugge (* 1949 in Cincinnati , Ohio ) is an American molecular biologist and cancer researcher . She has taught and researched at Harvard University since 1997 and is primarily concerned with research into breast and ovarian cancer .

Career

Joan Brugge began at the Northwestern University , a mathematics -Studies, but moved to the Department of Biology , when her older sister to a brain tumor sick. In 1971 she received her bachelor's degree in biology before moving to Baylor College of Medicine in Texas , where she earned a Ph.D. in virology in 1975. received his doctorate . She worked as a post-doc under Raymond L. Erikson at the University of Colorado Denver from 1975 to 1979 and was finally hired in July 1979 as an assistant professor of microbiology at Stony Brook University in New York . There she was promoted to full professor in 1988, but left the university a year later to continue to work in the same position at the University of Pennsylvania . In parallel, she conducted research on behalf of the Howard Hughes Medical Institute .

In 1992 Brugge moved into business and was employed as Scientific Director at ARIAD Pharmaceuticals , a pharmaceutical company focused on oncology . In 1997, however, she returned to the academic ranks by following the call of Harvard University and since then has been professor of cell biology . She has also headed the Harvard-based Ludwig Cancer Center since 2014 .

Scientific work

Brugges cancer research is mainly devoted to breast and ovarian tumors . Particular attention is paid to the investigation of resistance mechanisms in tumor cells and the identification of signal pathways in the cell cycle , for example in terms of oncogenes . In addition, her working group developed a method for growing cell cultures three-dimensionally using a gel in order to simulate the processes in vivo more precisely.

To date, Brugge has contributed to over 200 scientific publications.

Honors

Brugge has received numerous prizes for her scientific achievements to date, including the MERIT Award from the National Institutes of Health (2001), the Rosalind E. Franklin Award from the National Cancer Institute (2005) and the Charlotte Friend Award from the American Association for Cancer Research (2005) . She was also elected to the American Academy of Arts and Sciences in 2000 and the National Academy of Sciences in 2001 . She is also a member of the National Academy of Medicine and the American Association for Cancer Research.

literature

• Tiffany K. Wayne: American Women of Science since 1900. ABC-CLIO , 2011, pp. 263-265.

Web links

• Profile on the website of Harvard University (English)

Individual evidence

1. ↑ ^{a b} Sister's illness led her into biology. The Boston Globe , March 17, 2007, accessed December 14, 2017 . 
2. ↑ Book of Members 1780 – present, Chapter B. (PDF; 1.2 MB) In: American Academy of Arts and Sciences (amacad.org). Accessed December 14, 2017 .