Lloyd Felton

Lloyd Derr Felton (born  November 18, 1885 in Pine Grove Mills , Pennsylvania , †  September 11, 1953 in Baltimore ) was an American bacteriologist and immunologist . He worked from 1922 to 1935 as a professor at Harvard University and from 1935 to 1938 at Johns Hopkins University and from 1938 to 1949 at the National Institute of Health , including from 1944 as its medical director. His scientific achievements include the isolation of a pure antibody preparation from serum for the first time .

Life

Lloyd Felton was born in Pine Grove Mills and the state of Pennsylvania in 1885 . He earned an AB degree from the College of Wooster in 1910 and then completed a degree in medicine from Johns Hopkins University , which he graduated in 1916. After working there in the laboratory for bacteriology and immunology until 1919, he switched to the Rockefeller Institute for Medical Research .

From 1922 to 1935 he served as an assistant professor of preventive medicine and hygiene at Harvard University and then until 1938 as an associate professor of bacteriology and pathology at Johns Hopkins University. In the same year he moved to the United States Public Health Service , where he worked in the Infectious Diseases Division of the National Institute of Health in Bethesda, Maryland and was appointed medical director of the institute in 1944.

He retired five years later. He died in Baltimore in 1953 and was buried in Arlington National Cemetery.

Scientific work

Lloyd Felton, who published around 150 scientific publications during his career , devoted himself in particular to the production of antisera for the treatment of bacterial pneumonia and its prophylaxis through immunization with the appropriate antigens . In 1926 he succeeded in isolating a pure antibody preparation from serum for the first time .

In addition, he was engaged in methods of determining the optimal dose of antisera, as well as the development of sulfonamides and research into meningitis . Named after him is an observation called the Felton phenomenon on the immunological tolerance of laboratory mice to the injection of high doses of lipopolysaccharides from pneumococci . In 1947/1948 he served as President of the American Association of Immunologists .

Awards (selection)

The College of Wooster awarded Lloyd Felton an honorary doctorate in 1925 . He has also been named a Fellow of the American Association for the Advancement of Science , the American Medical Association, and the American Public Health Association .

Works (selection)

• The Intrameningeal Virulence of Microorganisms. New York 1920
• Standardization of Antipneumococcus Horse Sera and Concentrates. Washington 1937

literature

• Felton, Lloyd Derr, bacteriologist. James Terry White: The National Cyclopaedia of American Biography. Volume 40, New York 1967, p. 245
• Deaths: Felton, Lloyd Derr. In: Journal of the American Medical Association. 154 (8) / 1954. American Medical Association, p. 694, ISSN  0098-7484
• Necrology: Lloyd D. Felton. In: Chemical & Engineering News. 31 (39) / 1953. American Chemical Society, p. 4034, ISSN  0271-3586