Mandelin reagent

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With the mandelin reagent , also known as "vanadium sulfuric acid" , after the Russian chemist KF Mandelin, a simple spot analysis is carried out to identify alkaloids and other compounds. The reagent is made up in a ratio of 0.5–1 g of ammonium metavanadate per 100–200 ml of concentrated sulfuric acid . The United States Department of Justice recommends the exact composition of 1 g to 100 ml. It is mainly used for tests for ketamine and 4-methoxyamphetamine , but must be freshly prepared for correct detection.

Color change during the test with the mandelin reagent for various substances
substance colour
2C-T-7 chestnut brown to black
3,4-methylenedioxyamphetamine blue black
4-methoxyamphetamine reddish brown
Acetylcysteine yellow to green to light blue
Acetylsalicylic acid olive green
Ambroxol hydrochloride light green
Ascorbic acid lime green to light blue
Atropine sulfate brown to light green
Benzocaine purple to brown to red
Benzphetamine bright yellow-green
Bisacodyl violet
Chlorpromazine dark olive
Ciprofloxacin red-brown
Clotrimazole green yellow
Codeine dark olive
Dexpanthenol no color change
Dextroamphetamine medium blue green
Dextromethamphetamine dark yellowish green
Diclofenac sodium salt red-brown
Dimethoxy meth dark olive brown
Doxepin strong red-brown
Doxylamine yellow to blue green
Dristan gray olive
Exedrine dark olive
Fexofenadine hydrochloride dark red-brown
Fluoxetine hydrochloride gray-brown
Fluphenazine dihydrochloride red-brown
Glibenclamide yellow-greenish
Haloperidol light green turquoise
heroin medium red brown
Hydrochlorothiazide slightly greenish
Indomethacin yellow-green to black
Ketamine dark red orange
cocaine dark orange yellow
Lactulose brown
Mace medium olive green
MDMA blue black
Mescaline dark yellowish brown
Metformin orange
Methadone dark grayish blue
Methamphetamine hydrochloride yellow-green to blue
Methaqualone strong orange-yellow
Methylphenidate bright orange-yellow
Metoprolol tartrate violet
Metronidazole lemon yellow
Morphine monohydrate dark gray to reddish brown
Sodium chloride strong orange
Nitrofurantoin acid green
Noscapine brownish red
Omeprazole brown purple
opium olive black
Oxycodone dark greenish yellow
Paracetamol medium olive
Paramethoxymethamphetamine reddish brown
Pethidine hydrochloride Red orange
Phenazone light green
Phenoxymethylpenicillin yellow to blue
Phenprocoumon dark red
Pravastatin sodium salt dark purple
Prednisolone Brown black
Procaine dark orange
Propoxyphene dark reddish brown
Pyridoxal hydrochloride violet blue
Ramipril very strong green
Salicylic acid olive brown to green

See also

Individual evidence

  1. KF Mandelin: About vanadium sulfuric acid, a new reagent for alkoloids , (In: Pharm. Ztschr. F. Russl., 22, St. Petersburg, 1883, pp. 345–357), printed by E. Wienecke, 1883.
  2. ^ A b Charles F. Poe, DW O'Day: A study of Mandelin's test for strychnine . In: The Journal of the American Pharmaceutical Association . Volume 19, No. 12 , 1930, ISSN  0003-0465 , pp. 1292-1299 .
  3. a b Color Test Reagents / Kits for Preliminary Identification of Drugs of Abuse. NIJ Standard – 0604.01. National Institute of Justice, July 2000, accessed March 4, 2016 .
  4. Именные реактивы. xenoid.ru, accessed March 4, 2016 .
  5. a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj Peter Greulich: Script for the "Drug Analysis" internship in the 8th semester Pharmacy. July 2010, accessed March 4, 2016 .