Matthias Schwab (pharmacologist)

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Matthias Schwab (2018)

Matthias Schwab (born September 3, 1963 in Nuremberg ) is a German doctor and university lecturer. He is director of the Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology at the Robert Bosch Hospital in Stuttgart , an institution of the Robert Bosch Foundation , and holder of the Chair of Clinical Pharmacology at the University of Tübingen and Medical Director of the Department of Clinical Pharmacology at the University Hospital Tübingen .

Life

After graduating from the Dürer Gymnasium in Nuremberg , Schwab studied human medicine and obtained his doctorate in 1991 at the Institute for Toxicology and Pharmacology at the Friedrich-Alexander University Erlangen-Nuremberg with the dissertation Influence of subchronic treatment of mice with nifedipine on various P-450 isoenzyme activities Liver - comparison with enzyme activities of other species. After obtaining his license to practice medicine, he was qualified as a specialist in pediatric and adolescent medicine in 1996 and clinical pharmacology in 2000.

As part of his work as head of the clinical studies and drug information department at Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology, Stuttgart, he completed his habilitation in 2003 at the Eberhard Karls University of Tübingen on genetic factors for the prognosis and therapy of inflammatory bowel diseases . After a visiting professorship at St. Jude Children's Research Hospital in Memphis (Tennessee, USA), he took over the management of the Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology and the Chair of Clinical Pharmacology at the University of Tübingen, where he has also been a co-opted professor of the mathematical and natural science faculty since 2015 .

His main research interests are pharmacological genome research and its importance for personalized medicine . He is particularly interested in the application of new technologies in the context of pharmacogenomics, including epigenetic aspects in connection with cancer therapies and immunosuppressants .

Appointments as full professor for clinical pharmacology at the Medical University of Innsbruck , Austria (2006), as well as professor and chair holder for clinical pharmacology with simultaneous position as senior physician in the clinic at Karolinska University and Karolinska University Clinic , Sweden (2010), declined he off.

Awards

Offices and memberships

  • Since 2004: Full member and deputy chairman of the Commission for Drugs for Children and Young People at the Federal Institute for Drugs and Medical Devices (BfArM), Germany
  • Since 2004: Member of the ethics committee of the LÄK Baden-Württemberg
  • Since 2007: Member of the Drugs Commission of the German Medical Association (AKdÄ)
  • Since 2008: Member of the Pharmacogenetics Sub-Committee of the International Union of Basic and Clinical Pharmacology (IUPHAR)
  • Since 2010: Member, Deputy Chairman and since 2018 Chairman of the Drug Metabolism and Transporter Management Committee of the International Union of Basic and Clinical Pharmacology (IUPHAR)
  • Since 2010: First deputy director of the Natural Science and Medical Institute (NMI) at the University of Tübingen
  • 2010–2013: Member of the genetic diagnostics commission at the Federal Ministry of Health , Germany
  • 2010–2017: Member of the governing body of the European Association of Clinical Pharmacology (EACPT)
  • 2013–2018: Board member of the German Society for Clinical Pharmacology and Therapy eV (DGKliPha)
  • Since 2015: Chairman of the Medical Research Commission of the Academy of Sciences and Literature , Mainz
  • 2015/2018: President of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT)

Publications (as editor)

Periodicals

  • Editor-in-Chief Pharmacogenetics and Genomics . (with M. Ratain, USA)
  • Section Editor at Genome Medicine in the Pharmacogenomics & Personalized Medicine section.
  • Section editor at the monthly pediatric medicine. in the drug therapy section .

Monographs

  • M. Schwab, WP Kaschka, E. Spina (Eds.): Pharmacogenomics in Psychiatry. (= Advances in Biological Psychiatry. Vol. 25). Karger, 2010, ISBN 978-3-8055-9498-1 .
  • WH Seyberth, A. Rane, M. Schwab (Eds.): Pediatric Clinical Pharmacology. (= Handbook of Experimental Pharmacology. 205). Springer, 2011, ISBN 978-3-642-26989-9 .

Individual evidence

  1. ↑ a b Prof. Dr. med. Matthias Schwab , website of the Drugs Commission of the German Medical Association, accessed on July 6, 2018.
  2. ↑ a b c d e f g h i j k Curriculum Vitae Matthias Schwab, MD. Website of the Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology, accessed on July 5, 2018
  3. ↑ a b c Member entry by Prof. Dr. Matthias Schwab (with picture and CV) at the German Academy of Sciences Leopoldina , accessed on September 16, 2016.
  4. ↑ P. Fisel, E. Schaeffeler, M. Schwab: DNA Methylation of ADME Genes. In: Clinical pharmacology and therapeutics. Volume 99, Number 5, May 2016, pp. 512-527, doi: 10.1002 / cpt.343 . PMID 27061006 (Review).
  5. ↑ M. Schwab, UM Zanger, C. Marx, E. Schaeffeler, K. Klein, J. Dippon, R. Kerb, J. Blievernicht, J. Fischer, U. Hofmann, C. Bokemeyer, M. Eichelbaum: Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group. In: Journal of clinical oncology. Volume 26, number 13, May 2008, pp. 2131-2138, doi: 10.1200 / JCO.2006.10.4182 . PMID 18299612 .
  6. ↑ Cell death by gene variant. In: Doctors newspaper. November 16, 2005.
  7. ^ Academy of Sciences and Literature Mainz, list of members. Accessed September 15, 2016.
  8. ↑ Press release State Ministry, February 2, 2016
  9. ^ Clarivate Analytics
  10. ↑ Michael Herm: Top Medical Research - IKP Head Prof. Dr. Matthias Schwab receives the Robert Pfleger Prize. In: idw-online.de. June 20, 2016, accessed September 16, 2016 .
  11. ^ Clarivate Analytics
  12. ↑ Natural Science and Medical Institute (NMI) at the University of Tübingen ( Memento of the original from September 16, 2016 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.nmi.de
  13. ↑ DGKliPha
  14. ↑ Medical Research Commission , accessed September 15, 2016.
  15. ↑ Editorial Board , Retrieved July 5, 2018.
  16. ↑ Editorial Board , Retrieved July 5, 2018.
  17. ↑ Editorial Board , Retrieved July 5, 2018.
personal data
SURNAME Schwab, Matthias
BRIEF DESCRIPTION German physician and university professor
DATE OF BIRTH 3rd September 1963
PLACE OF BIRTH Nuremberg