Metaflumizone
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( E ) isomer | |||||||||||||||||||
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Non-proprietary name | Metaflumizone | ||||||||||||||||||
other names |
( EZ ) -2 '- [2- (4-cyanophenyl) -1- (α, α, α-trifluoro- m -tolyl) ethylidene] -4- (trifluoromethoxy) carbanilohydrazide |
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Molecular formula | C 24 H 16 F 6 N 4 O 2 | ||||||||||||||||||
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Mechanism of action |
Sodium channel antagonist |
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properties | |||||||||||||||||||
Molar mass | 506.40 g · mol -1 | ||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Metaflumizon is an insecticide from the semicarbazone group . The compound is a sodium channel - antagonist that affects the conduction of insects and thus leads to paralysis and death of insects.
Isomerism
There are two isomers of the active ingredient, the ( E ) isomer and the ( Z ) isomer. In technical metaflumizone, the isomer ratio ( E ) :( Z ) is about 9: 1.
Approval and trade names
Metaflumizon was approved as an ectoparasitic for dogs and cats in Germany . It was marketed as a monopreparation for cats under the trade name ProMeris , but has not been marketable since June 30, 2018. The same applies to the former combination preparation with Amitraz called ProMeris Duo .
In a number of EU countries, including Austria, but not in Germany and Switzerland, plant protection products with this active ingredient are permitted (trade name Alverde ).
Web links
- EPAR summary for the public: ProMeris (PDF file; 190 kB)
- Entry on metaflumizone in the ChemIDplus database of the United States National Library of Medicine (NLM)
Individual evidence
- ↑ a b c d e f g h i Metaflumizone data sheet at the Federal Office for Consumer Protection and Food Safety , accessed on May 14, 2017.
- ↑ a b Metaflumizone data sheet from Sigma-Aldrich , accessed on May 14, 2017 ( PDF ).
- ↑ General Directorate Health and Food Safety of the European Commission: Entry on metaflumizone in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 25, 2016.