Metolcarb

Structural formula
General
Surname	Metolcarb
other names	m -Tolyl- N -methyl carbamate; MTMC;
Molecular formula	C 9 H 11 NO 2
Brief description	colorless solid
External identifiers / databases
EC number	214-446-0
ECHA InfoCard	100.013.133
PubChem	14322
Wikidata	Q6824213
properties
Molar mass	165.19 g mol −1
Physical state	firmly
Melting point	77.7 ° C
Vapor pressure	145 mPa (25 ° C)
solubility	sparingly soluble in water (2.6 g l −1 at 20 ° C)
safety instructions
H and P phrases	H: 302-411
	P: 273
Toxicological data	268 mg kg −1 ( LD 50 , rat , oral ) ; 6000 mg kg −1 ( LD 50 , rabbit , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Metolcarb is a chemical compound from the group of carbamates . Metolcarb is used as an insecticide and works by inhibiting acetylcholinesterase .

Extraction and presentation

Metolcarb can be obtained through a multi-stage reaction. 3-methylphenol and phosgene react first . The product reacts further with methylamine to form Metolcarb.

Admission

The active ingredient metolcarb was never approved as a plant protection product in the EU. In Switzerland, too, no pesticides containing this active ingredient are permitted.

Individual evidence

↑ ^a ^b ^c ^d Entry on Metolcarb in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on December 13, 2013.
↑ ^a ^b ^c Entry on m-tolyl-N-methylcarbamate in the GESTIS substance database of the IFA , accessed on December 13, 2013 (JavaScript required)
↑ Entry on m-tolyl methylcarbamate in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Data metolcarb at Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).
↑ Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 87 ( limited preview in Google Book search).
↑ General Directorate Health and Food Safety of the European Commission: Entry on Metolcarb in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 26, 2016.

[ppdb-1] Entry on Metolcarb in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on December 13, 2013.

[GESTIS-2] Entry on m-tolyl-N-methylcarbamate in the GESTIS substance database of the IFA , accessed on December 13, 2013 (JavaScript required)

[CLP_100.013.133-3] Entry on m-tolyl methylcarbamate in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[Sigma-4] Data metolcarb at Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

[unger-5] Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 87 ( limited preview in Google Book search).

[6] General Directorate Health and Food Safety of the European Commission: Entry on Metolcarb in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 26, 2016.