Nitenpyram
Structural formula | ||||||||||||||||
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General | ||||||||||||||||
Surname | Nitenpyram | |||||||||||||||
other names |
( E ) - N - (6-chloro-3-pyridylmethyl) - N -ethyl- N '-methyl-2-nitrovinylidenediamine |
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Molecular formula | C 11 H 15 ClN 4 O 2 | |||||||||||||||
Brief description |
light yellow solid |
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properties | ||||||||||||||||
Molar mass | 270.72 g mol −1 | |||||||||||||||
Physical state |
firmly |
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density |
1.4 g cm −3 (bulk density) |
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Melting point |
82 ° C |
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solubility |
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safety instructions | ||||||||||||||||
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Toxicological data | ||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Nitenpyram is a chemical compound from the group of neonicotinoids .
Extraction and presentation
Like imidacloprid, nitenpyram can be obtained in a multi-stage reaction starting from 2-chloro-5-chloromethylpyridine .
properties
Nitenpyram is a light yellow crystalline solid that is soluble in water.
use
Nitenpyram is used as a systemic insecticide in livestock and in agriculture to control aphids and fleas , for example . The compound was discovered by Takeda Chemical Industries in 1989 and marketed by Novartis Animal Health in 1995 as a flea adulticide for oral use. It belongs to the group of acetylcholine receptors - agonists in the postsynaptic membranes. The acetylcholinesterase is not inhibited by nitenpyram. It is used under the trade name Capstar for the oral treatment of cat flea infestations in cats and dogs, but has no long-term effects. In the first hour after administration, when the product starts to work, the pet may experience increased itching, which is due to the increased activity of the fleas. This effect is temporary and quickly subsides when the fleas die.
Web links
Individual evidence
- ↑ a b c d e f g data sheet Nitenpyram, PESTANAL at Sigma-Aldrich , accessed on April 26, 2016 ( PDF ).
- ↑ a b c d e Entry on Nitenpyram in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on April 26, 2016.
- ↑ I. Yamamoto, JE Casida: Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor . Springer Science & Business Media, 2012, ISBN 978-4-431-67933-2 , pp. 113 ( limited preview in Google Book search).
- ↑ a b Entry on Nitenpyram at Vetpharm, accessed on April 26, 2016.
- ↑ vetcontact.com: Clinical - Vol. 23 No. 3 (A), March 2001 , accessed April 26, 2016.