Pyrazophos

Structural formula
General
Surname	Pyrazophos
other names	O , O -Diethyl- O- (5-methyl-6-carbethoxypyrazolo [1,5- a ] pyrimidyl-2) thiophosphate; 2- ( O , O -Diethylthionophosphoryl) -5-methyl-6-carbethoxy-pyrazolo [1,5- a ] -pyrimidine; Afugan; Curamil;
Molecular formula	C 14 H 20 N 3 O 5 PS
Brief description	white crystals; technical green to brown solid;
External identifiers / databases
EC number	236-656-1
ECHA InfoCard	100.033.310
PubChem	26033
Wikidata	Q302171
properties
Molar mass	373.37 g mol −1
Physical state	firmly
density	1.348 g cm −3
Melting point	51-52 ° C
boiling point	Decomposition from 160 ° C
solubility	very heavy in water (4.2 mg l −1 at 20 ° C)
safety instructions
H and P phrases	H: 301-332-410
	P: 273-301 + 310-501
Toxicological data	218 mg kg −1 ( LD 50 , rat , oral ) ; > 2000 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Pyrazophos is a chemical compound from the group of thiophosphoric acid esters and pyrazolpyrimidines , which has an insecticidal and fungicidal effect and was introduced in 1971 by Hoechst (now Bayer CropScience ).

use

Pyrazophos is used as a systemic fungicide in fruit , wine and vegetable cultivation against powdery mildew . It is also used to a lesser extent in cereal cultivation .

distribution

Pyrazophos is sold under the brand names Afugan and Curamil . It was also available in combination with propiconazole under the brand name Desgan and with flusilazole as Furesan .

Admission

In the EU , the approval was revoked in 2000 by the Commission . In Switzerland, too, no pesticides containing this active ingredient are permitted.

literature

H. Fehrmann: In Systemische Fungizide - an overview I. On the mode of action of substances customary in practice Journal of Phytopathology 1976 , 86 , 67-89.

Web links

WHO on Pyrazophos (PDF file; 1.65 MB)

Individual evidence

↑ ^a ^b Entry on Pyrazophos. In: Römpp Online . Georg Thieme Verlag, accessed on May 20, 2014.
↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on pyrazophos in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
↑ Entry on Pyrazophos in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Rudolf Heitefuss: In Crop Protection: Principles of practical Phytomedicine, 3rd revised and expanded edition, Georg Thieme Verlag Stuttgart ISBN 3-13-513303-6 .
↑ Decision of the Commission of March 9, 2000 on the non-inclusion of the active ingredient pyrazophos (PDF) in Annex I of Council Directive 91/414 / EEC and the revocation of the authorizations for plant protection products containing this active ingredient.
↑ General Directorate Health and Food Safety of the European Commission: Entry on Pyrazophos in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 27, 2016.

[roempp-1] Entry on Pyrazophos. In: Römpp Online . Georg Thieme Verlag, accessed on May 20, 2014.

[GESTIS-2] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on pyrazophos in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .

[CLP_100.033.310-3] Entry on Pyrazophos in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[4] Rudolf Heitefuss: In Crop Protection: Principles of practical Phytomedicine, 3rd revised and expanded edition, Georg Thieme Verlag Stuttgart ISBN 3-13-513303-6 .

[5] Decision of the Commission of March 9, 2000 on the non-inclusion of the active ingredient pyrazophos (PDF) in Annex I of Council Directive 91/414 / EEC and the revocation of the authorizations for plant protection products containing this active ingredient.

[6] General Directorate Health and Food Safety of the European Commission: Entry on Pyrazophos in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 27, 2016.