Pyrrole nitrine

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Structural formula
Structural formula of pyrrole nitrine
General
Non-proprietary name Pyrrole nitrine
other names

3-chloro-4- (3-chloro-2-nitrophenyl) -1 H -pyrrole ( IUPAC )

Molecular formula C 10 H 6 Cl 2 N 2 O 2
External identifiers / databases
CAS number 1018-71-9
EC number 213-812-7
ECHA InfoCard 100.012.557
PubChem 13916
Wikidata Q371817
Drug information
ATC code

D01 AA07

Drug class
properties
Molar mass 257.07 g · mol -1
Physical state

firmly

Melting point

124.5 ° C

safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
07 - Warning

Caution

H and P phrases H: 315-319-335
P: 261-305 + 351 + 338
Toxicological data
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Pyrrole nitrine is a chemical compound from the group of pyrrole derivatives.

use

Pyrrole nitrine is an antifungal antibiotic that was isolated from the bacterium Pseudomonas pyrrocinia . It is effective against various types of pathogenic fungi, including a .:

(see Trichophyton )

It blocks the electron transport between succinate or reduced NADH and coenzyme Q .

Its application is topical (local).

Individual evidence

  1. a b c Entry on pyrrole nitrine in the ChemIDplus database of the United States National Library of Medicine (NLM) .
  2. a b c Datasheet Pyrrolnitrin from Pseudomonas cepacia at Sigma-Aldrich , accessed on April 22, 2011 ( PDF ).
  3. Micutrin ® : Riassunto delle Caratteristiche del Prodotto (Summary of Product Characteristics), Pharmacia Italia SpA as of March 2002.

Trade names

Micutrin (Italy, except sales)