Pyrrole nitrine
Structural formula | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
General | ||||||||||||||||
Non-proprietary name | Pyrrole nitrine | |||||||||||||||
other names |
3-chloro-4- (3-chloro-2-nitrophenyl) -1 H -pyrrole ( IUPAC ) |
|||||||||||||||
Molecular formula | C 10 H 6 Cl 2 N 2 O 2 | |||||||||||||||
External identifiers / databases | ||||||||||||||||
|
||||||||||||||||
Drug information | ||||||||||||||||
ATC code | ||||||||||||||||
Drug class | ||||||||||||||||
properties | ||||||||||||||||
Molar mass | 257.07 g · mol -1 | |||||||||||||||
Physical state |
firmly |
|||||||||||||||
Melting point |
124.5 ° C |
|||||||||||||||
safety instructions | ||||||||||||||||
|
||||||||||||||||
Toxicological data | ||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Pyrrole nitrine is a chemical compound from the group of pyrrole derivatives.
use
Pyrrole nitrine is an antifungal antibiotic that was isolated from the bacterium Pseudomonas pyrrocinia . It is effective against various types of pathogenic fungi, including a .:
(see Trichophyton )
It blocks the electron transport between succinate or reduced NADH and coenzyme Q .
Its application is topical (local).
Individual evidence
- ↑ a b c Entry on pyrrole nitrine in the ChemIDplus database of the United States National Library of Medicine (NLM) .
- ↑ a b c Datasheet Pyrrolnitrin from Pseudomonas cepacia at Sigma-Aldrich , accessed on April 22, 2011 ( PDF ).
- ↑ Micutrin ® : Riassunto delle Caratteristiche del Prodotto (Summary of Product Characteristics), Pharmacia Italia SpA as of March 2002.
Trade names
Micutrin (Italy, except sales)