Roxarson
Structural formula | ||||||||||||||||
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General | ||||||||||||||||
Surname | Roxarson | |||||||||||||||
other names |
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Molecular formula | C 6 H 6 AsNO 6 | |||||||||||||||
Brief description |
yellow solid |
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properties | ||||||||||||||||
Molar mass | 263.04 g mol −1 | |||||||||||||||
Physical state |
firmly |
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Melting point |
> 300 ° C |
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solubility |
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safety instructions | ||||||||||||||||
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Toxicological data | ||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Roxarson is a chemical compound from the group of phenylarsonic acid derivatives that was discovered in 1941.
Extraction and presentation
Roxarson can be obtained by reacting sodium 4-hydroxyphenyl arsonate with sulfuric and nitric acid.
properties
Roxarson is a crystalline yellow solid. It decomposes when heated, producing nitrogen oxides and arsenic (III) oxide , among other things . The substance forms a mono-, di- and tri-sodium salt.
use
Roxarson is used as a veterinary growth stimulant (for pig and poultry feed) and for enteric infections, formerly for the production of arsphenamines and as a precipitation reagent of zirconium . Use in food-producing animals is banned in Europe, but allowed in the US and other countries.
literature
- Gladys S. Bayse, Latanya P. Hammonds-Odie, Kimberly M. Jackson, Deidre K. Tucker, Ward G. Kirlin: Permeation of roxarsone and its metabolites increases caco-2 cell proliferation. In: Advances in Biological Chemistry , 2013, 3 (4), p. 389, doi : 10.4236 / abc.2013.34041 .
Individual evidence
- ↑ a b c d e f g Entry on Roxarson in the GESTIS substance database of the IFA , accessed on September 29, 2017(JavaScript required) .
- ↑ a b c d e f Paul Heinz List, Ludwig Hörhammer: Chemicals and Drugs Part B: R, S . Springer-Verlag, 2013, ISBN 978-3-642-66377-2 , pp. 178 ( limited preview in Google Book search).
- ^ Steeve Giguere, John F. Prescott, Patricia M. Dowling: Antimicrobial Therapy in Veterinary Medicine . John Wiley & Sons, 2013, ISBN 978-1-118-67507-6 ( limited preview in Google Book Search).
- ^ J. Buckingham: Dictionary of Organic Compounds . CRC Press, 1985, ISBN 978-0-412-54090-5 , pp. 3760 ( limited preview in Google Book search).
- ↑ Spectrum of Science: Environmental Chemistry: Fattening Agent Responsible for Arsenic in Groundwater - Spectrum of Science , accessed on September 29, 2017.
- ↑ EU: Extract from the report of the Food and Veterinary Office on the inspection visit to South Africa , June 12-21, 2007
- ↑ Questions and Answers Regarding 3-Nitro (Roxarsone) "> Product Safety Information> Questions and Answers Regarding 3-Nitro (Roxarsone): Product Safety Information> Questions and Answers Regarding 3-Nitro (Roxarsone) , accessed on September 29, 2017.