Sulisobenzone

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Structural formula
Structural formula of sulisobenzone
General
Non-proprietary name Sulisobenzone
other names
  • 5-benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid
  • BENZOPHENONE-4 ( INCI )
Molecular formula C 14 H 12 O 6 S
Brief description

white solid

External identifiers / databases
CAS number 4065-45-6
EC number 223-772-2
ECHA InfoCard 100,021,612
PubChem 19988
ChemSpider 18829
DrugBank DB11185
Wikidata Q7636301
properties
Molar mass 308.31 g mol −1
Physical state

firmly

density

0.59 g cm −3 (26.4 ° C)

Melting point

145 ° C

boiling point

491 ° C

solubility

easily in water (313.7 g l −1 at 25 ° C)

safety instructions
GHS labeling of hazardous substances
07 - Warning

Caution

H and P phrases H: 315-319-412
P: 305 + 351 + 338
Toxicological data

3530 mg kg −1 ( LD 50ratoral )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Sulisobenzone (also benzophenone-4 ) is a chemical compound that, as a component of sun creams, protects the skin from UV-B and short-wave UV-A radiation .

The sodium salt , sulisobenzone sodium, is also known as BENZOPHENONE -5 (INCI).

Trade names

Uvinul MS40

Individual evidence

  1. Entry on BENZOPHENONE-4 in the CosIng database of the EU Commission, accessed on December 28, 2019.
  2. Data sheet 5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid, ≥97.0% (HPLC) from Sigma-Aldrich , accessed on June 30, 2014 ( PDF ).
  3. a b c d e Entry on sulisobenzone in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .
  4. a b Entry on sulisobenzone in the ChemIDplus database of the United States National Library of Medicine (NLM) .
  5. G. J. Nohynek, H. Schaefer: Benefit and risk of organic ultraviolet filters . In: Regul. Toxicol. Pharmacol. tape 33 , no. 3 , 2001, p. 285-299 , doi : 10.1006 / rtph.2001.1476 , PMID 11407932 .
  6. ^ Skin cancer foundation: Understanding UVA and UVB .