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{{Short description|Protein-coding gene in the species Homo sapiens}}
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{{Infobox_gene}}
'''Forkhead box protein D4''' is a [[protein]] that in [[Human|humans]] is encoded by the ''FOXD4'' [[gene]].<ref name="pmid7957066">{{cite journal | authorvauthors = Pierrou S, Hellqvist M, Samuelsson L, Enerback S, Carlsson P | title = Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending | journal = EMBO J | volume = 13 | issue = 20 | pages = 5002–12 | year date=Dec 1994 | month = Dec | pmid = 7957066 | pmc = 395442 | doi = 10.1002/j.1460-2075.1994.tb06827.x}}</ref><ref name="pmid8825632">{{cite journal | authorvauthors = Larsson C, Hellqvist M, Pierrou S, White I, Enerback S, Carlsson P | title = Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12) | journal = Genomics | volume = 30 | issue = 3 | pages = 464–9 | year date=Feb 1997 | month = Feb | pmid = 8825632 | pmc = | doi = 10.1006/geno.1995.1266 }}</ref><ref name="pmid12234674">{{cite journal | authorvauthors = Freyaldenhoven BS, Fried C, Wielckens K | title = FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines | journal = Gene | volume = 294 | issue = 1-21–2 | pages = 131–140 | year date=Sep 2002 | month = Sep | pmid = 12234674 | pmc = | doi =10.1016/S0378-1119(02)00702-3 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: FOXD4 forkhead box D4| url = httphttps://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2298| accessdate = }}</ref>
 
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==References==
{{reflist}}
 
==Further reading==
{{refbegin | 2}}
*{{cite journal | vauthors=Cederberg A, Betz R, Lagercrantz S |title=Chromosome localization, sequence analysis, and expression pattern identify FKHL 18 as a novel human forkhead gene. |journal=Genomics |volume=44 |issue= 3 |pages= 344–6 |year= 1997 |pmid= 9325056 |doi= 10.1006/geno.1997.4864 |display-authors=etal}}
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*{{cite journal | authorvauthors=GerhardFan DSY, WagnerNewman LT, FeingoldLinardopoulou EAE, ''etTrask al.''BJ |title=TheGene status, quality,content and expansionfunction of the NIHancestral full-lengthchromosome cDNAfusion project:site thein Mammalianhuman Genechromosome 2q13-2q14.1 and Collectionparalogous (MGC)regions. |journal=Genome Res. |volume=1412 |issue= 10B11 |pages= 2121–71663–72 |year= 20042003 |pmid= 1548933412421752 |doi= 10.1101/gr.2596504338402 | pmc=528928187549 }}▼
| citations =
*{{cite journal | authorvauthors=CederbergStrausberg ARL, BetzFeingold REA, LagercrantzGrouse S, ''et al.''LH |title=ChromosomeGeneration localization,and sequenceinitial analysis, andof expressionmore patternthan identify15,000 FKHLfull-length 18human asand a novel humanmouse forkheadcDNA genesequences. |journal=GenomicsProc. Natl. Acad. Sci. U.S.A. |volume=4499 |issue= 326 |pages= 344–616899–903 |year= 19972003 |pmid= 932505612477932 |doi= 10.10061073/genopnas.1997242603899 | pmc=139241 |display-authors=etal |bibcode=2002PNAS.4864..9916899M|doi-access=free }}
*{{cite journal | authorvauthors=FanHumphray YSJ, NewmanOliver TK, LinardopoulouHunt E, Trask BJAR |title=GeneDNA contentsequence and functionanalysis of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions9. |journal=Genome Res.Nature |volume=12429 |issue= 116990 |pages= 1663–72369–74 |year= 20032004 |pmid= 1242175215164053 |doi= 10.11011038/gr.338402nature02465 | pmc=1875492734081 |bibcode=2004Natur.429..369H |display-authors=etal}}
*{{cite journal | authorvauthors=StrausbergGerhard RLDS, FeingoldWagner EAL, GrouseFeingold LH, ''et al.''EA |title=GenerationThe andstatus, initialquality, and analysisexpansion of morethe than 15,000NIH full-length humancDNA andproject: mousethe cDNAMammalian Gene sequencesCollection (MGC). |journal=Proc.Genome Natl. Acad. Sci. U.S.ARes. |volume=9914 |issue= 2610B |pages= 16899–9032121–7 |year= 20032004 |pmid= 1247793215489334 |doi= 10.10731101/pnasgr.2426038992596504 | pmc=139241528928 |display-authors=etal}}
*{{cite journal | authorvauthors=HumphrayMinoretti SJP, OliverArra KM, HuntEmanuele AR, ''et al.''E |title=DNAA sequenceW148R andmutation analysisin ofthe human chromosomeFOXD4 9gene segregating with dilated cardiomyopathy, obsessive-compulsive disorder, and suicidality. |journal=NatureInt. J. Mol. Med. |volume=42919 |issue= 69903 |pages= 369–74369–72 |year= 20042007 |pmid= 1516405317273782 |doi= 10.10383892/nature02465 ijmm.19.3.369| pmcdisplay-authors=etal|doi-access=2734081free }}
▲*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Minoretti P, Arra M, Emanuele E, ''et al.'' |title=A W148R mutation in the human FOXD4 gene segregating with dilated cardiomyopathy, obsessive-compulsive disorder, and suicidality. |journal=Int. J. Mol. Med. |volume=19 |issue= 3 |pages= 369–72 |year= 2007 |pmid= 17273782 |doi= }}
}}
{{refend}}
 
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{{Transcription factors|g3}}
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Latest revision as of 06:52, 22 December 2023

FOXD4
Identifiers
AliasesFOXD4, FKHL9, FOXD4A, FREAC-5, FREAC5, forkhead box D4
External IDsOMIM: 601092; MGI: 1347467; HomoloGene: 83248; GeneCards: FOXD4; OMA:FOXD4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

2298

14237

Ensembl

ENSG00000170122

ENSMUSG00000051490

UniProt

Q12950

Q60688

RefSeq (mRNA)

NM_207305

NM_008022

RefSeq (protein)

NP_997188

NP_032048

Location (UCSC)Chr 9: 0.12 – 0.12 MbChr 19: 24.88 – 24.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Forkhead box protein D4 is a protein that in humans is encoded by the FOXD4 gene.[5][6][7][8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170122 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051490 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Pierrou S, Hellqvist M, Samuelsson L, Enerback S, Carlsson P (Dec 1994). "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending". EMBO J. 13 (20): 5002–12. doi:10.1002/j.1460-2075.1994.tb06827.x. PMC 395442. PMID 7957066.
  6. ^ Larsson C, Hellqvist M, Pierrou S, White I, Enerback S, Carlsson P (Feb 1997). "Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12)". Genomics. 30 (3): 464–9. doi:10.1006/geno.1995.1266. PMID 8825632.
  7. ^ Freyaldenhoven BS, Fried C, Wielckens K (Sep 2002). "FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines". Gene. 294 (1–2): 131–140. doi:10.1016/S0378-1119(02)00702-3. PMID 12234674.
  8. ^ "Entrez Gene: FOXD4 forkhead box D4".

Further reading[edit]



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