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Protein-coding gene in the species Homo sapiens
Forkhead box protein D4 is a protein that in humans is encoded by the FOXD4 gene .[5] [6] [7] [8]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000170122 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051490 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Pierrou S, Hellqvist M, Samuelsson L, Enerback S, Carlsson P (Dec 1994). "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending" . EMBO J . 13 (20): 5002–12. doi :10.1002/j.1460-2075.1994.tb06827.x . PMC 395442 . PMID 7957066 .
^
^ Freyaldenhoven BS, Fried C, Wielckens K (Sep 2002). "FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines". Gene . 294 (1–2): 131–140. doi :10.1016/S0378-1119(02)00702-3 . PMID 12234674 .
^ "Entrez Gene: FOXD4 forkhead box D4" .
Further reading
Cederberg A, Betz R, Lagercrantz S, et al. (1997). "Chromosome localization, sequence analysis, and expression pattern identify FKHL 18 as a novel human forkhead gene". Genomics . 44 (3): 344–6. doi :10.1006/geno.1997.4864 . PMID 9325056 .
Fan Y, Newman T, Linardopoulou E, Trask BJ (2003). "Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions" . Genome Res . 12 (11): 1663–72. doi :10.1101/gr.338402 . PMC 187549 . PMID 12421752 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9" . Nature . 429 (6990): 369–74. Bibcode :2004Natur.429..369H . doi :10.1038/nature02465 . PMC 2734081 . PMID 15164053 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Minoretti P, Arra M, Emanuele E, et al. (2007). "A W148R mutation in the human FOXD4 gene segregating with dilated cardiomyopathy, obsessive-compulsive disorder, and suicidality" . Int. J. Mol. Med . 19 (3): 369–72. doi :10.3892/ijmm.19.3.369 . PMID 17273782 .
(1) Basic domains
(1.1) Basic leucine zipper (bZIP )(1.2) Basic helix-loop-helix (bHLH )
Group A Group B Group C bHLH-PAS Group D Group E Group F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors