2-chlorophenol

Structural formula
General
Surname	2-chlorophenol
other names	2-CP; ortho -chlorophenol; o -chlorophenol; 2-monochlorophenol; 2-MCP; 2-hydroxychlorobenzene;
Molecular formula	C 6 H 5 ClO
Brief description	Flammable liquid with an unpleasant iodoform-like smell
External identifiers / databases
EC number	202-433-2
ECHA InfoCard	100.002.213
PubChem	7245
DrugBank	DB03110
Wikidata	Q176486
properties
Molar mass	128.56 g mol −1
Physical state	liquid
density	1.262 g cm −3
Melting point	7 ° C
boiling point	174 ° C
Vapor pressure	230 Pa (20 ° C)
pK s value	9.11
solubility	slightly soluble in water (28.5 g l −1 at 20 ° C)
Refractive index	1.5524 (20 ° C)
safety instructions
H and P phrases	H: 302 + 312 + 332-314-411
	P: 273-302 + 352-305 + 351 + 338
Toxicological data	40 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

2-chlorophenol is an unpleasant, toxic liquid that smells like iodoform and belongs to the group of substances called chlorophenols . It is used in the manufacture of medicines and dyes and as a disinfectant. The compound appears as a pollutant in the groundwater.

properties

2-chlorophenol is a colorless liquid that is often yellowish to brown in color due to impurities. The liquid is sparingly soluble in water and hardly inflammable: the ignition temperature is 550 ° C.

use

2-Chlorophenol is used as an intermediate in the production of dyes and chlorinated chlorophenols.

safety instructions

The substance decomposes at higher temperatures to form hydrogen chloride , carbon monoxide and carbon dioxide . 2-chlorophenol irritates eyes, respiratory tract and skin; a corrosive effect can occur at high concentrations. The toxicity manifests itself primarily in disorders of the central nervous system .

Web links

The degradation of 2-chlorophenol in an upflow anaerobic sludge blanket (UASB) reactor
Committee on the Mutagenicity of Chemicals in Food Consumer Products and the Environment: Review of Genotoxicity of Chlorophenols (PDF; 334 kB)
Factsheet (speclab)

Individual evidence

↑ Entry on chlorophenols. In: Römpp Online . Georg Thieme Verlag, accessed on June 15, 2014.
↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Entry on 2-chlorophenol in the GESTIS substance database of the IFA , accessed on January 9, 2019(JavaScript required) .
^ Fieser and Fieser: Organic Chemistry , 2nd Edition, Verlag Chemie, Weinheim 1982, ISBN 3-527-25075-1 .
↑ David R. Lide (Ed.): CRC Handbook of Chemistry and Physics . 90th edition. (Internet version: 2010), CRC Press / Taylor and Francis, Boca Raton, FL, Physical Constants of Organic Compounds, pp. 3-110.
↑ Entry on 2-chlorophenol in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Analytes - 2-chlorophenol. In: chromatography-online.org. Retrieved February 5, 2016 .

[1] Entry on chlorophenols. In: Römpp Online . Georg Thieme Verlag, accessed on June 15, 2014.

[GESTIS-2] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Entry on 2-chlorophenol in the GESTIS substance database of the IFA , accessed on January 9, 2019(JavaScript required) .

[3] Fieser and Fieser: Organic Chemistry , 2nd Edition, Verlag Chemie, Weinheim 1982, ISBN 3-527-25075-1 .

[CRC90_3_110-4] David R. Lide (Ed.): CRC Handbook of Chemistry and Physics . 90th edition. (Internet version: 2010), CRC Press / Taylor and Francis, Boca Raton, FL, Physical Constants of Organic Compounds, pp. 3-110.

[CLP_100.002.213-5] Entry on 2-chlorophenol in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[6] Analytes - 2-chlorophenol. In: chromatography-online.org. Retrieved February 5, 2016 .