2-diethylaminoethanol

Structural formula
General
Surname	2-diethylaminoethanol
other names	N , N -diethylethanolamine; 2-hydroxytriethylamine; DEAE; DEEA; DIETHYL ETHANOLAMINE ( INCI ) ;
Molecular formula	C 6 H 15 NO
Brief description	colorless liquid with an amine-like odor
External identifiers / databases
EC number	202-845-2
ECHA InfoCard	100.002.587
PubChem	7497
Wikidata	Q209373
properties
Molar mass	117.19 g mol −1
Physical state	liquid
density	0.88 g cm −3
Melting point	−70 ° C
boiling point	161 ° C
Vapor pressure	1.9 mbar (20 ° C)
solubility	miscible with water
Refractive index	1.4414 (20 ° C, 589 nm)
safety instructions
H and P phrases	H: 226-302-311 + 331-314
	P: 210-280-303 + 361 + 353-304 + 340 + 310-305 + 351 + 338-370 + 378
MAK	Switzerland: 10 ml m −3 or 50 mg m −3
Toxicological data	1300 mg kg −1 ( LD 50 , rat , oral ) ; 1110 mg kg −1 ( LD 50 , rabbit , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

2- (Diethylamino) ethanol is a chemical compound from the group of amino alcohols .

Extraction and presentation

Diethylethanolamine can be obtained by reacting diethylamine and ethylene oxide .

{\ displaystyle \ mathrm {(C_ {2} H_ {5}) _ {2} NH + (CH_ {2} CH_ {2}) O \ longrightarrow (C_ {2} H_ {5}) _ {2} NCH_ { 2} CH_ {2} OH}}

It is also possible to produce it by reacting diethylamine and ethylene chlorohydrin .

properties

2- (Diethylamino) ethanol is a slightly volatile, flammable, hygroscopic, colorless liquid with an ammonia-like odor, which is miscible with water. Your aqueous solution has a strong alkaline reaction.

use

2- (Diethylamino) ethanol is used as an intermediate in the manufacture of procaine .

Individual evidence

↑ Entry on DIETHYL ETHANOLAMINE in the CosIng database of the EU Commission, accessed on March 11, 2020.
↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Entry on 2- (diethylamino) ethanol in the GESTIS substance database of the IFA , accessed on July 23, 2016(JavaScript required) .
↑ Data sheet 2-Diethylaminoethanol (PDF) from Merck , accessed on November 12, 2012.
↑ Entry on 2-diethylaminoethanol in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Swiss Accident Insurance Fund (Suva): Limit values - current MAK and BAT values (search for 100-37-8 or 2-diethylaminoethanol ), accessed on November 2, 2015.
↑ Allen F. Bollmeier, Jr .: Alkanolamines . In: Jacqueline I. Kroschwitz (Ed.): Kirk-Othmer Encyclopedia of Chemical Technology , 4th. Edition, Volume 2, John Wiley & Sons, Inc., New York 1999, ISBN 978-0471419617 , pp. 1-34.
↑ Diethylaminoethanol . USDA. February 2, 2012. Retrieved on 8/28/2012.

[CosIng-1] Entry on DIETHYL ETHANOLAMINE in the CosIng database of the EU Commission, accessed on March 11, 2020.

[GESTIS-2] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Entry on 2- (diethylamino) ethanol in the GESTIS substance database of the IFA , accessed on July 23, 2016(JavaScript required) .

[Merck-3] Data sheet 2-Diethylaminoethanol (PDF) from Merck , accessed on November 12, 2012.

[CLP_100.002.587-4] Entry on 2-diethylaminoethanol in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[5] Swiss Accident Insurance Fund (Suva): Limit values - current MAK and BAT values (search for 100-37-8 or 2-diethylaminoethanol ), accessed on November 2, 2015.

[6] Allen F. Bollmeier, Jr .: Alkanolamines . In: Jacqueline I. Kroschwitz (Ed.): Kirk-Othmer Encyclopedia of Chemical Technology , 4th. Edition, Volume 2, John Wiley & Sons, Inc., New York 1999, ISBN 978-0471419617 , pp. 1-34.

[7] Diethylaminoethanol . USDA. February 2, 2012. Retrieved on 8/28/2012.