Arndt Borkhardt

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Arndt Borkhardt (born September 22, 1963 in Lübz ) is a German pediatrician , oncologist and immunologist .

Life

Arndt Borkhardt was born in Mecklenburg in 1963 as the son of the microbiologist Hertha-Lore Borkhardt . In 1982 he graduated from high school in Magdeburg . Then he did his basic military service in the NVA . In 1984 he began studying medicine at the Magdeburg Medical Academy . He completed his practical year 1989–1990, in addition to the training content surgery , internal medicine and pediatrics , in the field of physiology at the Magdeburg Institute for Neurobiology and Brain Research . In 1990 Borkhardt received his doctorate with a thesis on electrocortical correlates of memory performance . In 1990 Borkhardt became an assistant doctor at the children's clinic of the Magdeburg Medical Academy.

In January 1991 he received the molecular genetic research grant from the Stüssgen Schmidt Foundation and worked at the children's clinic at the Justus Liebig University in Giessen . He then began his specialist training there in May 1992 as a specialist in paediatrics , which he completed in 1997 and was appointed senior physician . Later he was appointed senior physician for neonatology and pediatric intensive care medicine at the Giessen clinic . In 1998 he was awarded the Adalbert Czerny Prize of the German Society for Child and Adolescent Medicine (DGKJ) for his work on molecular genetic studies of chromosomal aberrations in hematological neoplasms in childhood . Borkhardt completed his habilitation in 1999 with molecular genetic work on the development of leukemia in children and received the venia legendi in pediatrics at the University of Giessen. As a senior physician for pediatric hematology and oncology and head of the clinic's molecular genetic laboratory, he then worked at the facility until 2001. In 2003 he was appointed to the C3 professorship in Pediatric Hematology and Oncology, Stem Cell Transplantation at the Ludwig Maximilians University in Munich . He also became head of the hematological-oncological ward at von Hauner 's Children 's Hospital and head of training at the Bavarian Medical Association . In 2005 the German Academy of Sciences honored Leopoldina Borkhardt with the Carus Medal and the Carus Prize of the city of Schweinfurt .

Between 2005 and 2006 Borkhardt was appointed to the departments of General Pediatrics and Pediatric Hematology and Oncology at the University Hall (2005), Duisburg-Essen (2006), Jena (2006) and at the Heinrich-Heine University in Dusseldorf . Borkhardt accepted the latter position and has been Director of the Clinic for Pediatric Hematology, Oncology and Clinical Immunology at the University of Düsseldorf since November 2, 2006. Borkhardt has been a member of the Leopoldina Academic Academy since 2012 .

Borkhardt is married and has three daughters.

Fonts

  • with Irwin Reiss, Roswitha Füssle, Andreas Sziegoleit with Ludwig Gortner: Disinfectant contaminated with Klebsiella oxytoca as a source of sepsis in babies. In: The Lancet . 356 (2000), p. 310. PMID 11071189
  • with Ludwig Gortner and Irwin Reiss: Consequences of scientific reports of complications. In: Lancet. 356 (2000), p. 2015. PMID 11130555
  • Blocking oncogenes in malignant cells by RNA interference - new hope for a highly specific cancer treatment? In: Cancer Cell . 2 (2002), pp. 167-168. PMID 12242146
  • with Willi Woessmann and Xinbin Chen: Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines. In: Cancer Chemother Pharmacol . 50 (2002), pp. 397-404. PMID 15257933
  • with Kerstin Busch, Wilhelm Wössmann, Alfred Reiter and Jochen Harbott: Combined polymerase chain reaction methods to detect c-myc / IgH rearrangement in childhood Burkitt's lymphoma for minimal residual disease analysis. In: Haematologica . 89 (2004), pp. 818-825. PMID 15257933
  • with U. Fuchs: The application of siRNA technology to cancer biology discovery. In: Advances in Cancer Research . 96 (2007), pp. 75-102. PMID 17161677
  • with Markus Metzler, Jochen Bruch, Daniel Stachel, Thorsten Langer, Jochen Harbott and others: Temporary blast reduction after immunoglobulin administration for congenital cytomegalovirus infection masking infant leukemia with cryptic MLL rearrangement. In: Leukemia Research . 31 (2007), pp. 553-557. PMID 16814860
  • with K. Huck, O. Feyen, T. Niehues, F. Rüschendorf, N. Hübner, HJ Laws, T. Telieps, S. Knapp, HH Wacker, A. Meindl and H. Jumaa: Girls homozygous for an IL-2 -inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation. In: Journal of Clinical Investigation . 119 (2009), pp. 1350-1358. PMID 19425169

literature

Individual evidence

  1. ^ Czerny Prize Winner
  2. Leopoldina Academy honors Professor Dr. Arndt Borkhardt (Munich) with the Carus Medal
  3. Carus Prize of the City of Schweinfurt 2006 to Arndt Borkhardt and Oliver G. Schmidt. , Press release of the German Academy of Sciences Leopoldina
  4. Member entry by Prof. Dr. Arndt Borkhardt (with picture and CV) at the German Academy of Natural Scientists Leopoldina , accessed on July 1, 2016.