Bafinivirus

Bafinivirus
Systematics
Classification : Viruses Area : Riboviria Empire : Orthornavirae Phylum : Pisuviricota Class : Pisoniviricetes Order : Nidovirals Subordination : Tornidovirineae Family : Tobaniviridae Subfamily : Piscanivirinae Genre : Bafinivirus
Taxonomic characteristics
Genome : (+) ss RNA linear Baltimore : Group 4 Symmetry : complex Cover : available
Scientific name
Bafinivirus
Left
NCBI  Taxonomy: 694018 ViralZone ( ExPASy , SIB): 755 ICTV Taxon History: 201901883

Type of Bafinivirus (here WBV , type White bream virus ).

The virus genus Bafinivirus is a group of nidoviruses that have been isolated from bony fish .

In electron microscopy , diagnostic examinations in 2001 by employees of the Friedrich Loeffler Institute , a novel virus in Custer ( Blicca bjoerkna observed) that acts as an enveloped RNA virus has been detected in cell cultures was be multiplied and a very unusual, bazilliforme had shape. The shape was reminiscent of baculoviruses , rhabdoviruses or (due to the bulging envelope proteins ) of coronaviruses .

In 2006, John Ziebuhr's group succeeded in sequencing and fully molecular characterizing this virus, which was recognized as a new nidovirus. He also suggested the name for the new genus based on the particular morphology of the virus ( ba zilliformes Fi sch Ni dovirus). This white bream virus is the type species for the genus. Subsequently, further new nidoviruses in king salmon ( Oncorhynchus tshawytscha ) and golden minnow ( Pimephales promelas ) were discovered as possible new members of the Bafiniviruses.

Within the nidoviruses, they were initially closest to the toroviruses (genus Torovirus ), so that a separate genus and (to distinguish it from the morphologically classic coronaviruses ) a separate subfamily Torovirinae within the family Coronaviridae was created, which contained the Bafiniviruses. Later other species were added that were related to the Bafini and Toroviruses. As part of the further development of the Coronaviridae family and the order Nidovirales , the genus Bafiniviruses was then placed in a new family Tobaniviridae and a new subfamily Piscanivirinae within the order Nidovirales .

properties

The bafiniviruses are single-stranded RNA viruses with positive polarity ; their genome, with a length between 26.5 and 27 kB , is significantly smaller compared to other, classic corona viruses . Sequence comparisons showed an independent cluster formation and clear distance within the nidoviruses and to, like other mammalian coronaviruses, as well as the Roniviridae and Arteriviridae . The polycistronic genome of the Bafinivirus has five open reading frames . The virus isolation and characterization succeeded in Güster virus in cell culture with EPC cells . The virions are 170 to 200 nm long and 75 to 88 nm wide. Inside is an elongated capsid 120 to 150 nm long and 19 to 22 nm wide . On the viral envelope 20 appear to 25 nm long Peplomere .

Systematics

(*) Type type

• Order nidovirales

• Suborder Tornidovirineae

• Family Tobaniviridae

• Subfamily Piscanivirinae

• Genus Bafinivirus

• Subgenus Blicbavirus

• Art White bream virus (WBV, German Güster virus) (*)

• Subgenus Pimfabavirus

• Species Fathead minnow nidovirus 1 (German golden minnow nidovirus)

• Genus Oncotshavirus

• Subgenus Salnivirus

• Species Chinook salmon nidovirus 1 (German king salmon bafinivirus) (*)

literature

• H. Schütze, R. Ulferts, B. Schelle, S. Bayer, H. Granzow, B. Hoffmann, TC Mettenleiter, J. Ziebuhr: Characterization of White bream virus reveals a novel genetic cluster of nidoviruses. Journal of virology (2006) 80 (23): pp. 11598-11609, doi: 10.1128 / JVI.01758-06 , PMID 16987966 , PMC 1642614 (free full text).
• R. Ulferts, TC Mettenleiter, J. Ziebuhr: Characterization of Bafinivirus main protease autoprocessing activities. Journal of virology (2011) 85 (3): pp. 1348-1359, doi: 10.1128 / JVI.01716-10 , PMID 21068254 , PMC 3020504 (free full text).
• WN Batts, AE Goodwin, JR Winton: Genetic analysis of a novel nidovirus from fathead minnows. J. Gen. Virol. (2012) 93 (6): pp. 1247-1252 PMID 22422065

Individual evidence

1. ↑ ^{a b c d e f g h i j} ICTV: ICTV Taxonomy history: Bafinivirus
2. ↑ H. Granzow et al .: Identification and ultrastructural characterization of a novel virus from fish. J. Gen. Virol. (2001) 82 (12): pp. 2849-2859 PMID 11714959
3. ↑ H. Schütze et al .: Characterization of White Bream Virus Reveals a Novel Genetic Cluster of Nidoviruses. J. Virol. (2006) 80 (23): pp. 11598-11609
4. ↑ Proposal 2008.085-126V on ICTV revision № 2009: Revision of the family Coronaviridae. (PDF; 175 kB) 2008.085-126V. In: ICTV homepage . International Committee on Taxonomy of Viruses (ICTV), accessed May 5, 2020 . 
5. ↑ Database entry and associated revision proposal:
   • E INTRAG : ICTV taxonomy history: Bafinivirus . In: Virus Taxonomy . International Committee on Taxonomy of Viruses , accessed August 14, 2020 . 
   • P ROPOSAL : J. Ziebuhr, R. S. Baric, S. Baker, R. J. de Groot, C. Drosten, A. Gulyaeva, B. L. Haagmans, B. W. Neuman, S. Perlman, L. L. M. Poon, I. Sola, A. E. Gorbalenya: Reorganization of the family Coronaviridae into two families, Coronaviridae (including the current subfamily Coronavirinae and the new subfamily Letovirinae ) and the new family Tobaniviridae (accommodating the current subfamily Torovirinae and three other subfamilies), revision of the genus rank structure and introduction of a new subgenus rank . Proposal. In: International Committee on Taxonomy of Viruses (Ed.): Files  > Approved Proposals  > Animal ssRNA + Viruses  > 2017.001S.012-017S.R.Nidovirales (entry) . History. Revision 2018a. EC 50, Washington, DC February 18, 2017, Proposal Code  2017.013S (English, ictvonline.org [ ZIP ; 5.1 MB ; accessed on May 7, 2020]).
6. ↑ ^{a b c d e f g h i j k l m} ICTV: ICTV Master Species List 2019.v1. MSL # 35, March 2020

Web links

• Electron microscopic images of the WBV