Colorado tick fever
| Classification according to ICD-10 | |
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| A93.2 | Colorado tick fever |
| ICD-10 online (WHO version 2019) | |
The Colorado tick fever is a viral disease caused by ticks is transmitted. Pathogen is a virus of the Reoviridae family , the Colorado tick fever virus . Due to the way it is transmitted, it is assigned to the group of arboviruses .
Pathogen
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| Colorado tick fever virus | ||||||||||||||||||||
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The Colorado tick fever virus , and Colorado tick Feaver virus (CTFV) , is a non-enveloped virus with a double-stranded RNA as a genome . The genome is divided into 12 segments (segmented). The virions (virus particles) of the members of the genus Coltivirus are composed of two concentric, icosahedral capsids with a diameter of about 60-80 nm . The majority of the particles are not enveloped, but occasionally some particles are packed with a virus envelope when discharged via the Golgi apparatus .
Two serotypes (California CTFV-Ca and Florio CTFV-Fl ') can be distinguished among the currently 22 isolates of CTFV . The second species within the genus Coltivirus is Eyach virus , which was found in ticks in Europe and can potentially cause disease in humans.
See also: virus taxonomy
Epidemiology
The Colorado tick fever is in mountainous areas over 1700 meters in USA and Canada endemic ( Rocky Mountains ). Due to its limited range and unspecific symptoms, Colorado tick fever is still often referred to as mountain fever today . The virus is transmitted by various types of ticks, but mainly by Dermacentor variabilis . The main reservoirs for pathogens are mice and gray squirrels , but also sheep and deer .
Infections
After an incubation period of approx. 4 days, a mild biphasic fever (dromedary type) develops. A fleeting rash develops in 10% of cases . Meningo- encephalitis very rarely develops . Fatal courses are rare. Because viraemia often lasts for months, the disease can also be transmitted through blood transfusions. The convalescence is often tedious.
Therapy and prophylaxis
There is no specific therapy or vaccination .
swell
- ↑ ICTV Master Species List 2018b v1 MSL # 34, Feb. 2019
- ↑ a b c d e ICTV: Bluetongue virus , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)
- ↑ [1]