Crimidin

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Structural formula
Structural formula of crimidin
General
Surname Crimidin
other names
  • 2-chloro-4-dimethylamino-6-methylpyrimidine
  • 2-chloro- N , N , 6-trimethyl-4-pyrimidinamine
Molecular formula C 7 H 10 ClN 3
Brief description

colorless, odorless crystals

External identifiers / databases
CAS number 535-89-7
EC number 208-622-6
ECHA InfoCard 100.007.840
PubChem 10813
Wikidata Q2645488
properties
Molar mass 171.63 g · mol -1
Physical state

firmly

Melting point

87 ° C

boiling point

140-147 ° C (5.3 mbar )

solubility

heavy in water (9.36 g l −1 )

safety instructions
GHS hazard labeling from  Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary
06 - Toxic or very toxic

danger

H and P phrases H: 300
P: 301 + 310 + 330
Toxicological data

1.25 mg kg −1 ( LD 50 ,  rat ,  oral )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Crimidine is a pyrimidine derivative and vitamin B 6 - antagonist . Crimidin leads to a disturbance of the CNS via the glutamic acid metabolism and triggers convulsions .

It was commercially available until 1983 as "Castrix poison grains" and "Castrix pellets".

use

Crimidin was used as a rodenticide, in particular to control field mice .

Prohibition

There is a ban on the use of crimidin in Germany. Crimidin is not approved as a rodenticide in any EU country or Switzerland.

Individual evidence

  1. ↑ a b c d e f Entry on crimidin in the GESTIS substance database of the IFA , accessed on July 23, 2016(JavaScript required) .
  2. ↑ a b B. Janalík, E. Wohlgemuth: The Accumulation of crimidine in Some Fish organ . In: Acta Hydrochimica et Hydrobiologica . tape 14 , no. 1 , 1986, pp. 27 , doi : 10.1002 / aheh.19860140105 (English, PDF ).
  3. ↑ Entry on Crimidine in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
  4. ↑ Ordinance on the use of plant protection products .
  5. ↑ General Directorate Health and Food Safety of the European Commission: Entry on Crimidine in the EU pesticide database; Entry in the national directory of plant protection products in Switzerland ; accessed on February 14, 2016.