Cyanophos

Structural formula
General
Surname	Cyanophos
other names	O - (4-cyanophenyl) O , O -dimethyl thiophosphate; Thiophosphoric acid O - (4-cyanophenyl) O , O -dimethyl ester; Ciafos;
Molecular formula	C 9 H 10 NO 3 PS
Brief description	yellow to reddish yellow liquid with a weak, characteristic odor
External identifiers / databases
EC number	220-130-3
ECHA InfoCard	100.018.301
PubChem	17522
Wikidata	Q1147014
properties
Molar mass	243.22 g mol −1
Physical state	liquid
density	1.255–1.265 g cm −3 (25 ° C)
Melting point	14-15 ° C
boiling point	119 ° C (decomposition)
solubility	sparingly soluble in water (46 mg l −1 at 30 ° C)
Refractive index	1.5404 (32 ° C)
safety instructions
H and P phrases	H: 312-302-410
	P: 273-280-501
Toxicological data	215 mg kg −1 ( LD 50 , rat , oral ) ; 800 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Cyanophos is a chemical compound from the group of nitriles and thiophosphoric acid esters .

Extraction and presentation

Cyanophos can be obtained by reacting 4-cyanophenol with dimethylchlorothiophosphate (DMPCT).

properties

Cyanophos is a yellow to reddish yellow (according to another source colorless) liquid with a weak, characteristic odor, which is sparingly soluble in water. It decomposes from a temperature of 119 ° C.

use

Cyanophos is an organophosphate - insecticide that is used to contain a series of biting and sucking pests in cotton, fruit and vegetables. It acts as a cholinesterase inhibitor and is metabolized to 4-cyanophenol in plants and animals .

In Switzerland, Austria and Germany, no pesticides are approved that contain cyanophos as an active ingredient.

Trade names

Cyanox

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on Cyanophos in the GESTIS substance database of the IFA , accessed on July 22, 2011(JavaScript required) .
↑ David R. Lide (Ed.): CRC Handbook of Chemistry and Physics . 90th edition. (Internet version: 2010), CRC Press / Taylor and Francis, Boca Raton, FL, Physical Constants of Organic Compounds, pp. 3-118.
↑ Entry on Cyanophos in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ ^a ^b data sheet Cyanophos, PESTANAL ^® , analytical standard at Sigma-Aldrich , accessed on May 19, 2017 ( PDF ).
↑ Thomas A. Unger: Pesticide synthesis handbook . 1996, ISBN 978-0-8155-1401-5 ( page 315 in the Google book search).
^ Terence Robert Roberts, DH Hutson: Metabolic pathways of agrochemicals . Royal Soc of Chemistry, 1999, ISBN 978-0-85404-499-3 ( page 251 in Google book search).
^ Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 12, 2016.

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on Cyanophos in the GESTIS substance database of the IFA , accessed on July 22, 2011(JavaScript required) .

[CRC90_3_118-2] David R. Lide (Ed.): CRC Handbook of Chemistry and Physics . 90th edition. (Internet version: 2010), CRC Press / Taylor and Francis, Boca Raton, FL, Physical Constants of Organic Compounds, pp. 3-118.

[CLP_100.018.301-3] Entry on Cyanophos in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[Sigma-4] ta sheet Cyanophos, PESTANAL ^® , analytical standard at Sigma-Aldrich , accessed on May 19, 2017 ( PDF ).

[unger-5] Thomas A. Unger: Pesticide synthesis handbook . 1996, ISBN 978-0-8155-1401-5 ( page 315 in the Google book search).

[buch-6] Terence Robert Roberts, DH Hutson: Metabolic pathways of agrochemicals . Royal Soc of Chemistry, 1999, ISBN 978-0-85404-499-3 ( page 251 in Google book search).

[PSM-7] Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 12, 2016.