Diisopropyl ether

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Structural formula
Structural formula of diisopropyl ether
General
Surname Diisopropyl ether
other names
  • Isopropyl ether
  • Diisopropyl oxide
  • 2-isopropoxypropane
  • 2-propan-2-yloxypropane
Molecular formula C 6 H 14 O
Brief description

colorless liquid with an ethereal odor

External identifiers / databases
CAS number 108-20-3
EC number 203-560-6
ECHA InfoCard 100.003.237
PubChem 7914
Wikidata Q418989
properties
Molar mass 102.18 g mol −1
Physical state

liquid

density

0.72 g cm −3 (20 ° C)

Melting point

−86 ° C

boiling point

69 ° C

Vapor pressure

175 hPa (20 ° C)

solubility

poor in water (12 g l −1 at 20 ° C)

Refractive index

1.3658 (25 ° C)

safety instructions
GHS hazard labeling from  Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary
02 - Highly / extremely flammable 07 - Warning

danger

H and P phrases H: 225-336
EUH: 019-066
P: 210-233-240-403 + 235
MAK

DFG / Switzerland: 200 ml m −3 or 850 mg m −3

Toxicological data
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Diisopropyl ether (DIPE), often also referred to as isopropyl ether (IPE), is a colorless liquid . It is a solvent for animal, vegetable and mineral oils , fats , waxes and some natural resins .

Properties and use

IPE is generally not considered a solvent for synthetic resins, although it will dissolve ethyl cellulose and, in the presence of low molecular weight alcohols , cellulose nitrate as well . IPE tends - like many other ethers - to form peroxides , whereby these are already formed with IPE when standing in the dark for a long time. To prevent this, hydroquinone or IONOL (a mixture of antioxidants ) is added.

Safety-related parameters

Diisopropyl ether forms highly flammable vapor-air mixtures. The compound has a flash point of −28 ° C. The explosion range lies between 1.0% by volume (45 g / m 3 ) as the lower explosion limit (LEL) and 21% by volume (900 g / m 3 ) as the upper explosion limit (UEL). The maximum explosion pressure is 9.3 bar. The limit gap width was determined to be 0.94 mm (50 ° C). This results in an assignment to explosion group IIA. The ignition temperature is 405 ° C. The substance therefore falls into temperature class T2.

use

Diisopropyl ether is used as an extractant in the pharmaceutical and chemical industries. It is used as a substitute for diethyl ether when a solvent with lower volatility is desired.

safety instructions

With low acute toxicity, IPE has an anesthetic effect on humans and animals, similar to diethyl ether , but also shows almost the same negative effects as muscle contractions, spasms, nausea and a pronounced excitement phase.

Isomerism

Di- n -propyl ether is structural isomer to diisopropyl ether (di- i- propyl ether).

The isomeric di- n- propyl ether.

Individual evidence

  1. a b c d e f g h i Entry on diisopropyl ether in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
  2. David R. Lide (Ed.): CRC Handbook of Chemistry and Physics . 90th edition. (Internet version: 2010), CRC Press / Taylor and Francis, Boca Raton, FL, Physical Constants of Organic Compounds, pp. 3-186.
  3. Entry on diisopropyl ether in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
  4. Swiss Accident Insurance Fund (Suva): Limit values ​​- current MAK and BAT values (search for 108-20-3 or diisopropyl ether ), accessed on November 2, 2015.
  5. a b c Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19 (10), 1975, p. 55.
  6. ^ Union Carbide Data Sheet. Vol. 4/10/1968.
  7. ^ TH Brock: Safety and health protection in the laboratory: The application of the guidelines for laboratories. Springer, 1997, ISBN 978-3-540-61952-9
  8. ^ A b c d e E. Brandes, W. Möller: Safety-related parameters - Volume 1: Flammable liquids and gases , Wirtschaftsverlag NW - Verlag für neue Wissenschaft GmbH, Bremerhaven 2003.