Emil R. Unanue
Emil Raphael Unanue (born September 13, 1934 in Havana , Cuba ) is a Cuban - American pathologist and immunologist .
Life
Unanue earned a bachelor's degree in Havana in 1952 and graduated from the University of Havana with a degree in medicine in 1960 . 1961/1962 he worked as an assistant doctor in pathology at the Presbyterian University Hospital in Pittsburgh , Pennsylvania . Between 1962 and 1970 he conducted research in experimental pathology at the Scripps Research Institute in La Jolla , California - interrupted by a stay from 1966 to 1968 in the Department of Immunology at the National Institute for Medical Research in London district of Mill Hill . From 1970 to 1984 he was Professor of Immunopathology at Harvard University Medical School in Boston , Massachusetts . After two visiting professorships at the Kuwait University School of Medicine (1982) and the Royal Postgraduate Medical School in London (1983) - now Imperial College London - Unanue moved to Washington University in St. Louis , Missouri in 1985 . There he became professor of pathology and at the same time chief physician for pathology at the Barnes Jewish Hospital . Since 2000 he has also been a professor at Tulane University in New Orleans , Louisiana .
Act
Unanue was able to gain fundamental knowledge about the activation of T cells and their regulation. He was able to show that T cells do not recognize entire pathogenic germs, but rather small fragments that are presented to them together with MHC class II molecules by antigen-presenting cells (including macrophages ). In doing so, he created the basis for an understanding of how the immune system recognizes pathogens as a whole , and the basis for new studies of the pathophysiology of infectious and autoimmune diseases .
Awards (selection)
- 1980 Guggenheim Fellowship
- 1987 membership in the National Academy of Sciences
- 1989 William B. Coley Award
- 1989 membership in the American Academy of Arts and Sciences
- 1995 Albert Lasker Award for Basic Medical Research
- 1995 membership in the Institute of Medicine
- 1998 Chairman of the Microbiology and Immunology Section of the National Academy of Sciences
- 2000 Gairdner Foundation International Award
- 2005 Robert Koch Medal
Web links
- Emil Unanue, MD at Washington University in St. Louis (wustl.edu); Retrieved April 21, 2011
- Unanue, Emil Raphael ( Memento from October 19, 2006 in the Internet Archive ) at the ISI Web of Knowledge (isiknowledge.com); Retrieved April 21, 2011
Individual evidence
- ^ William B. Coley Award. In: cancerresearch.org. Retrieved January 24, 2016 .
- ↑ Book of Members 1780–2010 (PDF, 47 kB) of the American Academy of Arts and Sciences (amacad.org); Retrieved April 21, 2011
- ^ Albert Lasker Basic Medical Research Award 1995 Winners at laskerfoundation.org; Retrieved April 21, 2011
- ^ Emil Unanue BS, MD at the Gairdner Foundation (gairdner.org); Retrieved December 15, 2012
- ^ Winner of the Robert Koch Gold Medal since 1960 ( memento of October 7, 2007 in the Internet Archive ) at robert-koch-stiftung.de; Retrieved April 21, 2011
| personal data | |
|---|---|
| SURNAME | Unanue, Emil R. |
| ALTERNATIVE NAMES | Unanue, Emil Raphael; Unanue, Emil |
| BRIEF DESCRIPTION | Cuban-American pathologist and immunologist |
| DATE OF BIRTH | September 13, 1934 |
| PLACE OF BIRTH | Havana , Cuba |