Hans-Dieter Klenk

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Hans-Dieter-Klenk, 2017

Hans-Dieter Klenk (born June 25, 1938 in Cologne ) is a German virologist , recipient of the Robert Koch Medal , university professor and long-time director of the Institute for Virology in Marburg .

Life

Klenk, the son of Ernst Klenk , studied medicine from 1958 to 1963 at the universities of Tübingen , Vienna and Cologne . In 1964 he was awarded the grade summa cum laude for Dr. med. PhD. From 1964 to 1967 he completed a postgraduate course in biochemistry at the University of Tübingen. In 1971 he completed his habilitation in virology at the University of Giessen .

While he was working on his habilitation thesis, he initially worked for three years (1967–1970) at New York's Rockefeller University as a guest investigator in Purnell W. Choppin 's laboratory . From 1970 he was a research assistant for another three years at the Institute for Medical Virology at the University of Giessen, where he worked closely with Rudolf Rott . There he was appointed C3 professor in 1973. He held this professional position for almost twelve years until he was appointed as a C4 professorship and institute director at the Philipps University of Marburg in 1985 .

Hans-Dieter Klenk is married and has three adult sons.

Scientific research focus

The focus of the research, Hans-Dieter Klenk has devoted himself with his staff, are the influenza virus and the Marburg and Ebola virus . In the work, the structure and reproduction of these viruses were elucidated and important knowledge gained about the mechanisms that are responsible for the pathogenicity of the pathogens and for their transmission from animals to humans. In addition, this work formed the basis for the development of vaccines and antiviral drugs against the Ebola virus and other important pathogens.

Memberships in scientific societies

Awards

Appointments (selection)

  • DFG research group "Functional domains of membrane proteins", chairman 1989–1991
  • DFG Collaborative Research Center 286 "Intracellular Transport and Maturation of Proteins", Chairman 1991–2002
  • DFG Priority Program 1130 "Endothelial Infections", Chairman 2002–2006
  • Feldberg Foundation for Anglo-German Scientific Exchange, board member 1998–2000; Chairman 2000–2006
  • German-Israeli Committee (MINERVA), review committee, member, 1990–1999
  • European Molecular Biology Organization (EMBO), member since 1983
  • University structure commission of the state of Thuringia, medical committee, chairman, 1991–1993
  • Chemotherapeutic Research Institute Georg-Speyer-Haus, Frankfurt am Main, Scientific Advisory Board, member 1988–1994, member of the board 1994–2002
  • WHO Expert Advisory Panel on Virus Diseases, Member, 1989-1993
  • Leopoldina National Academy of Sciences, member since 1994
  • International Congress of Virology, International Advisory Program Committee, member, 1993, 1996, 1999
  • Virology Division of International Union of Microbiology Societies, Deputy. Chairman 1999–2002, Chairman 2002–2005
  • Society for Virology, President, 1999–2005
  • Institute of Medical Microbiology, Fudan University, Shanghai, China, International Scientific Advisory Board, Chairman 2004–2018
  • Pasteur Institute, Chinese Academy of Sciences, Shanghai, Scientific Advisory Board, member 2004–2012
  • Von Behring-Röntgen-Stiftung , Gießen-Marburg, Vice President, 2007- present
  • NIH Influenza Research Center, Emory University, Atlanta, USA, Scientific Advisory Board, member 2008 - current

Honors and prizes

Editorships and advisory board activities

Fonts (selection)

  • Hans-Dieter Klenk and Rudolf Rott: The molecular biology of influenza virus pathogenicity. Adv. Virus Res. Volume 34, 1988, pp. 247-281, doi: 10.1016 / s0065-3527 (08) 60520-5
  • Hans-Dieter Klenk and Wolfgang Garten: Host cell proteases controlling virus pathogenicity. Trends in Microbiology 2, 1994, pp. 39-43, doi: 10.1016 / 0966-842x (94) 90123-6
  • Hans-Dieter Klenk: Will we have and why do we need an Ebola vaccine? Nature Medicine 6, 2000, pp. 1322-1323, doi: 10.1038 / 82126
  • Hans-Dieter Klenk and Stephan Becker: Ebola virus vaccines: preparing for the unexpected. Science 349, 2015, pp. 693-694, doi: 10.1126 / science.aad0681
  • Hans-Dieter Klenk and Heinz Feldmann (Eds.): Ebola and Marburg viruses: molecular and cellular biology . Wymondham: Horizon Bioscience, c2004. 369 p. ISBN 0-9545232-3-7 .
  • Hans-Dieter Klenk (Ed.): Virology 12th . (Virology International congress 12th: 2002 Jul: Paris) Virus research, ISSN  0168-1702  ; vol 92 no 2 Elsevier, 2003.
  • Live Attenuated Recombinant Vaccine Protects Nonhuman Primates Against Ebola and Marburg Viruses . Department of Defense. Defense Technical Information Center [United States]: army medical research institute of infectious diseases fort detrick md, 2005.
  • Eva Böttcher-Friebertshäuser, Wolfgang Garten, Hans-Dieter Klenk (Eds.): Activation of Viruses by Host Proteases, Springer International Publishing AG, 2018, 335p., ISBN 978-3-319-75473-4 .
  • Hans-Dieter Klenk, Mikhail Matrosovich, Jürgen Stech (Eds.): Avian Influenza, Monographs in Virology 27, 292p., Karger, Basel, 2008

Over 500 independent scientific publications have appeared in specialist journals, in English. Most of them do not even appear when searching via traditional national bibliography search services such as the KVK , but they do appear via Google Scholarship.

Web links

Individual evidence

  1. ↑ Viola Düwert: Highly deserved appreciation for the lifetime achievement of Prof. Dr. Klenk. Marburg virologist receives the Robert Koch Gold Medal for his life's work. Philipps University of Marburg , May 3, 2006, accessed on February 24, 2011 .
  2. ↑ Viola Düwert: Ernst Jung Medal for Medicine in Gold 2008 for Prof. Dr. Hans-Dieter Klenk. Lifetime work of the 69-year-old virologist awarded. Philipps University of Marburg , January 9, 2008, accessed on February 24, 2011 .
  3. ^ Johannes Scholten: Hans-Dieter Klenk receives Emil von Behring Prize. Philipps University of Marburg , May 25, 2010, accessed on February 24, 2011 .
personal data
SURNAME Klenk, Hans-Dieter
BRIEF DESCRIPTION German virologist
DATE OF BIRTH June 25, 1938
PLACE OF BIRTH Cologne