Isofetamide

Structural formula
General
Surname	Isofetamide
other names	N - [1,1-Dimethyl-2- (4-isopropoxy- o -tolyl) -2-oxoethyl] -3-methylthiophene-2-carboxamide
Molecular formula	C 20 H 25 NO 3 S
Brief description	odorless white solid
External identifiers / databases
EC number	694-975-5
ECHA InfoCard	100.223.286
PubChem	71657865
ChemSpider	27473807
Wikidata	Q19286296
properties
Molar mass	359.48 g mol −1
Physical state	firmly
density	1.23 g cm −3 (bulk density)
Melting point	103 ° C
boiling point	176 ° C (decomposition)
solubility	poorly soluble in water (5 mg l −1 at 20 ° C); readily soluble in xylene , acetone and ethyl acetate ;
safety instructions
H and P phrases	H: 332-373-411
	P: ?
Toxicological data	> 2000 mg kg −1 ( LD 50 , rat , oral ) ; > 2000 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Isofetamide is a chemical compound from the group of phenyloxoethylthiophenamides .

properties

Isofetamide is an odorless white solid that is poorly soluble in water.

use

Isofetamide is used as a fungicide . The active ingredient inhibits succinate dehydrogenase .

Admission

Since 7 October 2019 drug is the first time in Germany with the pesticides approved Kenja for salads, spinach and herbs in greenhouse cultivation. No pesticides containing this active ingredient are permitted in Austria or Switzerland. In 2014, the compound was approved in Canada primarily against fungi of the genera Botrytis and Sclerotinia .

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k Entry on isofetamide in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on February 12, 2015.
^ ^A ^b ^c Pest Management Regulatory Agency Health Canada: Proposed Registration Decision Isofetamid PRD2014-19 , August 29, 2014, accessed February 12, 2015.
↑ Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A labeling of 3-methyl-N- {2-methyl-1- [2-methyl-4- (propan-2-yloxy) phenyl] -1-oxopropan-2-yl} thiophenes is shown, which is derived from a self-classification by the distributor -2-carboxamide in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on November 25, 2019.

↑ BVL: BVL - Approval Reports - Kenja (008663-00 / 00) , accessed on November 13, 2019

↑ General Directorate Health and Food Safety of the European Commission: Entry on isofetamide in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on December 6, 2019.

[PPDB-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k Entry on isofetamide in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on February 12, 2015.

[PMRAHC-2] A ^b ^c Pest Management Regulatory Agency Health Canada: Proposed Registration Decision Isofetamid PRD2014-19 , August 29, 2014, accessed February 12, 2015.

[3] Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A labeling of 3-methyl-N- {2-methyl-1- [2-methyl-4- (propan-2-yloxy) phenyl] -1-oxopropan-2-yl} thiophenes is shown, which is derived from a self-classification by the distributor -2-carboxamide in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on November 25, 2019.

[bvl.bund.de-4] BVL: BVL - Approval Reports - Kenja (008663-00 / 00) , accessed on November 13, 2019

[PSM-5] General Directorate Health and Food Safety of the European Commission: Entry on isofetamide in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on December 6, 2019.