Kevan M. Shokat

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Kevan M. Shokat (* 1964 ) is an American cell biologist and biochemist at the University of California, San Francisco .

Life

Shokat earned a BA in Chemistry from Reed College in Portland , Oregon in 1986 and a Ph.D. in 1991 from Peter G. Schultz at the University of California, Berkeley . , also in chemistry. He worked as a postdoctoral fellow with Christopher C. Goodnow at Stanford University in Stanford , California .

In 1994 Shokat received a first professorship (assistant professor) for chemistry at Princeton University in Princeton , New Jersey , in 1998 he became an associate professor . Since 1999 he has worked at both the University of California, Berkeley , and the University of California, San Francisco . He is currently (as of 2014) Professor (Chair) of cellular and molecular pharmacology at the University of California, San Francisco. He is also a professor of chemistry at the University of California, Berkeley. Since 2005 Shokat has also been doing research for the Howard Hughes Medical Institute (HHMI).

Act

Shokat is one of the leading figures in the field of chemical genetics . He uses methods of bio-organic chemistry to elucidate pathways of signal transduction at the level of the individual cell or the whole organism, which cannot be determined with biochemical or genetic methods alone. He is particularly concerned with the effect of individual protein kinases on the entire proteome in order to develop potential drugs against , for example, asthma , various forms of cancer , neurological disorders , bacterial infections , drug addiction or chronic pain syndrome . The organic low molecular weight compounds that inhibit certain kinases should have the lowest possible risk of failure in later clinical studies due to their selectivity . Methods have also been developed to accelerate the development of the target substances.

Awards (selection)

Web links

Individual evidence

  1. ↑ Kevan M. Shokat, PhD at the Michael J. Fox Foundation (michaeljfox.org); Retrieved May 29, 2014
  2. ↑ Eli Lilly Award in Biological Chemistry , winner 1935 to 2014 (PDF; 46 kB); Retrieved May 29, 2014
  3. ↑ Kevan M. Shokat at the National Academy of Sciences (nasonline.org); Retrieved May 29, 2014
  4. ↑ Book of Members 1780 – present (PDF, 1.3 MB) at the American Academy of Arts and Sciences (amacad.org); Retrieved May 29, 2014
personal data
SURNAME Shokat, Kevan M.
ALTERNATIVE NAMES Shokat, Kevan
BRIEF DESCRIPTION American cell biologist and biochemist
DATE OF BIRTH 1964