Copper (II) citrate

Structural formula
General
Surname	Copper (II) citrate
other names	Cupri citras; Kupzit;
Molecular formula	C 12 H 10 Cu 3 O 14
Brief description	light blue solid
External identifiers / databases
EC number	641-381-9
ECHA InfoCard	100.169.194
PubChem	61514
ChemSpider	4953985
Wikidata	Q1291820
properties
Molar mass	568.84 g mol −1 (anhydrous)
Physical state	firmly
solubility	poorly soluble in water
safety instructions
GHS hazard labeling ; no classification available
GHS hazard labeling ; no classification available
Toxicological data	1580 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Copper (II) citrate is the copper salt of citric acid .

description

Copper citrate is a crystalline, odorless solid , with a blue color characteristic of copper compounds. It is sparingly soluble in water.

Manufacturing

Copper citrate can be produced, for example, by reacting copper (II) hydroxide (Cu (OH) ₂ ) with citric acid:

{\ displaystyle \ mathrm {3 \ Cu (OH) _ {2} +2 \ C_ {6} H_ {8} O_ {7} \ rightarrow Cu_ {3} (C_ {6} H_ {5} O_ {7} ) _ {2} +6 \ H_ {2} O}}

Alternatively, copper citrate can also be obtained through the electrochemical conversion of citric acid and copper diluted with water.

use

Copper citrate is used in oenology to treat the “ Böckser ” wine defect - an odor and aroma defect . Copper citrate is added to the wine as granulated "kupzite" (with 5% copper citrate content). However, this leads to the fact that free copper ions with a completely inadequate taste then remain in the wine. After the Böckser treatment, these must therefore be intercepted with potassium hexacyanidoferrate (II) , which largely converts the free copper ions into an insoluble form that can therefore be filtered off from the wine.

Copper citrate is also used as an algicide in swimming pools, as an antiseptic , in metalworking oils and as a pigment since 1849 . The citrate is used to a small extent to preserve wood. In dietary supplements , it is for the trace element copper as a component.

safety instructions

In hamsters , Cu (II) citrate showed teratogenic effects after administration to pregnant animals , predominantly malformations of the cardiovascular system . The acute lethal dose in rats after oral ingestion is 1,580 mg kg ⁻¹ .

literature

AJ Davison, RT Hamilton: Stimulation of cytochrome oxidation by a copper citrate complex. In: Arch. Biochem. Biophys. Volume 126, 1968, pp. 228-231; PMID 5671065 .
Abdelaziz Madinzia, Mohammed El Amanea, Hamid Atmani: Synthesis, characterization and electrochemical properties of the copper citrate complexes. In: Annales de Chimie Science des Materiaux. Volume 25, 2000, pp. 179-185; doi: 10.1016 / S0151-9107 (00) 88893-5 .
FJ Di Carlo: Syndromes of cardiovascular malformations induced by copper citrate in hamsters. In: Teratology . Volume 21, 1980, pp. 89-101. PMID 7385058 .

Individual evidence

↑ ^a ^b copper chemicals. ( Memento of May 31, 2015 in the Internet Archive ) (PDF; 1.1 MB) p. 11.
^ ^A ^b Dale L. Perry: Handbook of Inorganic Compounds, Second Edition . Taylor & Francis US, 2011, ISBN 1-4398-1462-7 , pp. 139 ( limited preview in Google Book search).
↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
↑ ^a ^b Entry on copper (II) citrate in the ChemIDplus database of the United States National Library of Medicine (NLM) .
↑ Siegmar Görtges: Böckserbeseitigung with copper citrate . In: German viticulture . No. 20 , October 2, 2009, p. 24-25 ( PDF ).
^ N. Eastaugh, V. Walsh, T. Chaplin, R. Siddall: Pigment Compendium: A Dictionary of Historical Pigments. Butterworth-Heinemann, 2004, ISBN 978-0-7506-5749-5 .
^ TG Townsend, HM Solo-Gabriele: Environmental Impacts of Treated Wood. CRC Press, 2006, ISBN 978-0-8493-6495-2 .
↑ MJ Derelanko, MA Hollinger: Handbook of Toxicology. CRC Press, 2002, ISBN 978-0-8493-0370-8 .
^ NRC (USA) : Mineral Tolerance of Domestic Animals. National Academy of Sciences , Washington, 1980.

[tib-1] copper chemicals. ( Memento of May 31, 2015 in the Internet Archive ) (PDF; 1.1 MB) p. 11.

[Dale_L._Perry-2] A ^b Dale L. Perry: Handbook of Inorganic Compounds, Second Edition . Taylor & Francis US, 2011, ISBN 1-4398-1462-7 , pp. 139 ( limited preview in Google Book search).

[NV-3] This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.

[chemid-4] Entry on copper (II) citrate in the ChemIDplus database of the United States National Library of Medicine (NLM) .

[5] Siegmar Görtges: Böckserbeseitigung with copper citrate . In: German viticulture . No. 20 , October 2, 2009, p. 24-25 ( PDF ).

[6] N. Eastaugh, V. Walsh, T. Chaplin, R. Siddall: Pigment Compendium: A Dictionary of Historical Pigments. Butterworth-Heinemann, 2004, ISBN 978-0-7506-5749-5 .

[7] TG Townsend, HM Solo-Gabriele: Environmental Impacts of Treated Wood. CRC Press, 2006, ISBN 978-0-8493-6495-2 .

[8] MJ Derelanko, MA Hollinger: Handbook of Toxicology. CRC Press, 2002, ISBN 978-0-8493-0370-8 .

[9] NRC (USA) : Mineral Tolerance of Domestic Animals. National Academy of Sciences , Washington, 1980.