1-dodecanol

Structural formula
General
Surname	1-dodecanol
other names	Lauryl alcohol; 1-dodecanol; Dodecan-1-ol; LAURYL ALCOHOL ( INCI ) ;
Molecular formula	C 12 H 26 O
Brief description	white, pasty solid with a characteristic odor
External identifiers / databases
EC number	203-982-0
ECHA InfoCard	100.003.620
PubChem	8193
ChemSpider	7901
DrugBank	DB06894
Wikidata	Q161617
properties
Molar mass	186.34 g mol −1
Physical state	firmly
density	0.83 g cm −3
Melting point	24 ° C
boiling point	261 ° C
Vapor pressure	1.69 Pa (30 ° C)
solubility	practically insoluble in water (4 mg l −1 at 25 ° C); soluble in ethanol , mineral oil , vegetable oil and diethyl ether ;
safety instructions
H and P phrases	H: 319-410
	P: 273-305 + 351 + 338
Toxicological data	> 12800 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Dodecanol , also 1-dodecanol , dodecan-1-ol or trivial lauryl alcohol , belongs to the homologous series of alcohols and is hydrophobic or lipophilic . Dodecanol is solid, colorless and does not dissolve in water. The common name is lauryl alcohol, whose root word -lauryl- is also used for esters of dodecanol.

Occurrence

Dodecanol occurs naturally in the essential oil of Hyperici flos recens (fresh St. John's wort flowers) and Hyperici herba ( St. John's wort ).

Extraction and presentation

Dodecanol can be obtained from methyl isobutyl ketone .

use

It is used in the manufacture of surfactants and in pharmacology . It is also a component of cooling lubricants in metal processing.

Individual evidence

↑ Entry on LAURYL ALCOHOL in the CosIng database of the EU Commission, accessed on January 14, 2020.
↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on 1-dodecanol in the GESTIS substance database of the IFA , accessed on January 14, 2020(JavaScript required) .
↑ Entry on dodecan-1-ol. In: Römpp Online . Georg Thieme Verlag, accessed on December 28, 2014.
↑ Data sheet 1-Dodecanol from AlfaAesar, accessed on February 9, 2009 ( PDF )(JavaScript required) .
↑ Rudolf Hänsel, Konstantin Keller, Horst Rimpler, Georg Schneider: Hager's handbook of pharmaceutical practice, drugs E-O . Springer-Verlag, 2013, ISBN 978-3-642-57993-6 , pp. 482 ( limited preview in Google Book search).
↑ Xueru Sheng, Ning Li, Guangyi Li, Wentao Wang, Aiqin Wang, Y. and Cong, Xiaodong Wang, Tao Zhang: Direct Synthesis of Renewable Dodecanol and Dodecane with Methyl Isobutyl Ketone over Dual-Bed Catalyst Systems. In: ChemSusChem. 10, 2017, p. 825, doi : 10.1002 / cssc.201601563 .
↑ Werner Baumann, Bettina Herberg-Liedtke: Chemicals in metal processing Data and facts on environmental protection . Springer-Verlag, 2013, ISBN 978-3-642-61004-2 , p. 398 ( limited preview in Google Book search).

[CosIng-1] Entry on LAURYL ALCOHOL in the CosIng database of the EU Commission, accessed on January 14, 2020.

[GESTIS-2] ↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on 1-dodecanol in the GESTIS substance database of the IFA , accessed on January 14, 2020(JavaScript required) .

[3] Entry on dodecan-1-ol. In: Römpp Online . Georg Thieme Verlag, accessed on December 28, 2014.

[alfa-4] Data sheet 1-Dodecanol from AlfaAesar, accessed on February 9, 2009 ( PDF )(JavaScript required) .

[Rudolf_Hänsel,_Konstantin_Keller,_Horst_Rimpler,_Georg_Schneider-5] Rudolf Hänsel, Konstantin Keller, Horst Rimpler, Georg Schneider: Hager's handbook of pharmaceutical practice, drugs E-O . Springer-Verlag, 2013, ISBN 978-3-642-57993-6 , pp. 482 ( limited preview in Google Book search).

[DOI10.1002/cssc.201601563-6] Xueru Sheng, Ning Li, Guangyi Li, Wentao Wang, Aiqin Wang, Y. and Cong, Xiaodong Wang, Tao Zhang: Direct Synthesis of Renewable Dodecanol and Dodecane with Methyl Isobutyl Ketone over Dual-Bed Catalyst Systems. In: ChemSusChem. 10, 2017, p. 825, doi : 10.1002 / cssc.201601563 .

[Werner_Baumann,_Bettina_Herberg-Liedtke-7] Werner Baumann, Bettina Herberg-Liedtke: Chemicals in metal processing Data and facts on environmental protection . Springer-Verlag, 2013, ISBN 978-3-642-61004-2 , p. 398 ( limited preview in Google Book search).