Max Jaffé (pharmacologist)
Max Jaffé (born July 25, 1841 in Grünberg in Silesia , † October 26, 1911 in Berlin ) was a German physician and pharmacologist of Jewish descent. From 1873 until his death he was the first full professor of pharmacology at the Albertus University in Königsberg . Is named after him as a Jaffésche Kreatininprobe described analytical reaction for the quantitative determination of creatinine .
Life
Max Jaffé was born in Grünberg in Silesia in 1841 and graduated from high school in Breslau . From 1858 he studied medicine at the University of Berlin , where among other things Ludwig Traube and Wilhelm Kühne , where he with the issue in 1862 the identity of the Hämatoidins and Bilifulvins About doctorate , were among his academic teachers. After a study trip that took him to Prague , Vienna and Paris , he went in 1865 to work as an assistant to Ernst von Leyden at the University of Königsberg , where he headed the clinical laboratory of the medical clinic. In 1867 he received his habilitation in internal medicine . In addition to his work at the university, he ran a doctor's practice. In the years 1870/1871 he took part as a doctor in the Franco-German War , in which he was awarded the Iron Cross second class.
In 1872 he received an extraordinary professorship for medicinal chemistry . A year later he became the first full professor of pharmacology at Königsberg University and, in 1878, head of the laboratory for medicinal chemistry and experimental pharmacology belonging to the pathological institute. With Ernst Neumann , the director of the Pathological Institute, and Ernst Leopold Salkowski , an institute employee , Jaffé had a fruitful collaboration in the field of blood research , in particular for the detection of bone marrow-related "myelogenic" leukemia . From 1910 the laboratory headed by Jaffé existed as an independent pharmacological institute.
Max Jaffé died in Berlin in 1911 . His grave is in the Jewish cemetery in Berlin-Weißensee .
Scientific work
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Max Jaffé's research focused, among other things, on the importance and metabolism of certain chemical compounds such as urobilin , urocanic acid , indican and creatinine in the animal and human organism, as well as the biotransformation of exogenous substances and chemical analysis , in particular for the detection and isolation of components of urine . A quantitative detection reaction known as Jaffé's creatinine sample is named after him . From 1883 he was a member of the German Academy of Sciences Leopoldina .
literature
- Heinz Walter: Jaffe, Max. In: New German Biography (NDB). Volume 10, Duncker & Humblot, Berlin 1974, ISBN 3-428-00191-5 , p. 291 f. ( Digitized version ).
- Jaffé, Max. In: Julius Pagel : Biographical lexicon of outstanding doctors of the nineteenth century. Urban & Schwarzenberg, Berlin and Vienna 1901, p. 814
- Otto Cohnheim: Max Jaffe. In: Hoppe-Seyler's journal for physiological chemistry . 77/1912. Publishing house K. J. Trübner Strasbourg, pp. I / II.
- Doris Schwarzmann-Schafhauser: Jaffé, Max. In: Werner E. Gerabek u. a. (Ed.): Encyclopedia of medical history. De Gruyter, Berlin / New York 2005, ISBN 3-11-015714-4 , pp. 687 f.
Web links
- Literature by and about Max Jaffé in the catalog of the German National Library
Individual evidence
- ↑ Chemical examination of the bone marrow. In: Ernst Neumann: Blood and Pigments. Gustav Fischer, Jena 1917, p. 39.
| personal data | |
|---|---|
| SURNAME | Jaffé, Max |
| BRIEF DESCRIPTION | German pharmacologist and biochemist |
| DATE OF BIRTH | July 25, 1841 |
| PLACE OF BIRTH | Grünberg in Silesia |
| DATE OF DEATH | October 26, 1911 |
| Place of death | Berlin |