Mexacarbate

Structural formula
General
Surname	Mexacarbate
other names	4-dimethylamino-3,5-xylylmethyl carbamate; Zectran;
Molecular formula	C 12 H 18 N 2 O 2
Brief description	white, odorless crystals
External identifiers / databases
EC number	206-249-3
ECHA InfoCard	100.005.683
PubChem	9414
ChemSpider	9043
Wikidata	Q6825702
properties
Molar mass	222.29 g mol −1
Physical state	firmly
Melting point	85 ° C
safety instructions
H and P phrases	H: 300-312-410
	P: ?
Toxicological data	14 mg kg −1 ( LD 50 , rat , oral ) ; > 500 mg kg −1 ( LD 50 , rabbit , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Mexacarbate is a chemical compound from the group of carbamates and an insecticide , which was developed in 1961 by Alexander Shulgin at Dow Chemical .

Extraction and presentation

Mexacarbate can be obtained by reacting 4-amino-3,5-xylenol (3,5-dimethyl-4-aminophenol), dimethyl sulfate and methyl isocyanate .

use

Zectran preparation with mexacarbate as an active ingredient

Mexacarbate is a carbamate insecticide with a broad spectrum of activity. It also works as an acaricide and molluscicide . Mexacarbate is not approved as a crop protection ingredient in the European Union or Switzerland . The World Health Organization classifies mexacarbate as a pesticide active ingredient currently (2009) discontinued.

Individual evidence

↑ ^a ^b ^c ^d ^e Entry on Mexacarbate in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
↑ Entry on Mexacarbate in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ ^a ^b Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 88 ( limited preview in Google Book search).
↑ Richard W. Meikle: Metabolism of 4-Dimethylamino-3,5-Xylyl methylcarbamate (mexacarbate, active ingredient of Zectran® insecticide): A unified picture . In: Bull. Environ. Contam. Toxicol. tape 10 , no. 1 , July 1973, p. 29-36 , doi : 10.1007 / bf01684751 .
^ Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national directory of plant protection products in Switzerland ; Retrieved June 20, 2016.
↑ WHO: Active ingredients believed to be obsolete or discontinued for use as pesticides , in The WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2009 (PDF; 2.2 MB).

[GESTIS-1] Entry on Mexacarbate in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .

[CLP_100.005.683-2] Entry on Mexacarbate in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[unger-3] Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 88 ( limited preview in Google Book search).

[4] Richard W. Meikle: Metabolism of 4-Dimethylamino-3,5-Xylyl methylcarbamate (mexacarbate, active ingredient of Zectran® insecticide): A unified picture . In: Bull. Environ. Contam. Toxicol. tape 10 , no. 1 , July 1973, p. 29-36 , doi : 10.1007 / bf01684751 .

[5] Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national directory of plant protection products in Switzerland ; Retrieved June 20, 2016.

[6] WHO: Active ingredients believed to be obsolete or discontinued for use as pesticides , in The WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2009 (PDF; 2.2 MB).