Richard K. Gershon

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Richard "Dick" Keve Gershon (born December 24, 1932 in New York City , † July 11, 1983 in New Haven , Connecticut ) was an American immunologist .

Life

Gershon earned a bachelor's degree in biology from Harvard College in 1954 and an MD from Yale University School of Medicine in 1959 . His dissertation was entitled Disturbances in the Gestation of the Rat Caused by Reserpine and Attempts at Compensatory Hormono-Therapy . As a student he already had a research stay at the University of Paris and as a postdoctoral fellow he worked with Fred Prince at a virus and rickettsial research laboratory in Japan. Back at Yale University Gershon assistant was in pathology at Averill Liebow Abraham and Harry Greene SN before 1964 lecturer, 1966 assistant professor , 1970 associate professor and in 1976 full professor of pathology and director of the Department of Immunology was. In the meantime he was visiting professor at the Chester Beatty Research Institute in London in 1967/1968 . In 1977 Gershon was also director of the Institute for Cellular Immunology at the Howard Hughes Medical Institute in Yale and in 1978 he was also appointed a professor of biology at Yale University.

Gershon was married and had a daughter. He died of lung cancer .

Act

In 1970 Richard Gershon and Kazunari Kondo discovered that certain lymphocytes from the thymus ( T cells ) are able to suppress an immune response and called this population of T lymphocytes suppressor T cells . In addition, Gershon was able to show that these suppressor T cells are responsible for the phenomenon of acquired immune tolerance . Gershon discovered the feedback inhibition of the immune response, was able to show the role of the suppressor T cells for humoral and cellular immunity, analyzed the feedback mechanisms of inducer T cells and effector T cells and clarified the meaning of the V H - and MHC genes for their regulation. Most recent work has dealt with counter-suppressor T cells, which under certain conditions inhibit suppressor T cells.

Awards (selection)

Yale University has held regular Gershon honor seminars since 1987, the Gershon Memorial Seminars .

literature

Web links

Individual evidence

  1. ↑ Dr. Richard Gershon, Leader in Research on Immune System. , The New York Times , July 13, 1983
  2. ^ Richard K. Gershon MD at the Gairdner Foundation (gairdner.org); Retrieved January 24, 2013
  3. ^ William B. Coley Award. In: cancerresearch.org. Retrieved January 24, 2016 .
  4. ↑ Seminars & Events of the Department of Immunobiology at Yale University (yale.edu); Retrieved January 24, 2013
personal data
SURNAME Gershon, Richard K.
ALTERNATIVE NAMES Gershon, Richard; Gershon, Dick; Gershon, Richard Kive
BRIEF DESCRIPTION American immunologist
DATE OF BIRTH December 24, 1932
PLACE OF BIRTH New York City
DATE OF DEATH July 11, 1983
Place of death New Haven (Connecticut)