Stefanie Dimmeler
Stefanie Dimmeler (born July 18, 1967 in Ravensburg ) is a German biologist and biochemist . In 2005 she received the prize worth 1.55 million euros Gottfried Wilhelm Leibniz Prize for their research on programmed cell death of the endothelial cells of humans.
Life
Stefanie Dimmeler attended schools in Hagnau and Stetten as well as the grammar school in Markdorf . From 1986 to 1991 she studied biology at the University of Konstanz , where she completed her diploma in 1991 on the influence of Ebselen on Ca 2+ currents in human platelets at the Department of Biological Chemistry. In 1993 she also received her doctorate in Konstanz on nitric oxide-stimulated ADP-ribosylation for Dr. rer. nat.
From 1993 to 1995 Dimmeler was a scientific assistant in the Biochemical and Experimental Department of the Surgical Institute of the University of Cologne and then from 1995 to 2001 in the Medical Clinic, Department of Cardiology , University of Frankfurt am Main , where she has been the working group "Molecular Cardiology" since 1997 "directs. 1998 habilitation they are in specialist Experimental Medicine on endothelial dysfunction in atherosclerosis - studies on apoptosis of endothelial cells . Since 2001 she has held a professorship for molecular cardiology at the University of Frankfurt. Since 2008 she has been director of the Institute for Cardiovascular Regeneration at the Center for Molecular Medicine at Goethe University Frankfurt. From 2008 to 2012 she was a member of the German Ethics Council . In 2017 Stefanie Dimmeler was elected a member of the Leopoldina .
Stefanie Dimmeler has been the deputy site spokesperson for the "German Center for Cardiovascular Research eV" (DZHK) at the RheinMain site since 2011 . The DZHK is a partner of the German Centers for Health Research , which are committed to improving prevention, diagnosis and treatment of common diseases and was founded in 2011 on the initiative of the Federal Ministry of Education and Research . The aim of all six German Centers for Health Research is to bring results from basic research into clinical application more quickly.
In addition, Stefanie Dimmeler spokeswoman for the "Cardio-Pulmonary Institute," one of about 40 million euros from 2019 to 2026 funded Center of Excellence of the DFG .
research
Stefanie Dimmeler's research focuses primarily on the molecular biological investigation of endothelial cells , i.e. the cells that represent the lining of blood vessels . An essential aspect is the apoptosis , also known as programmed cell death, of the tissue. In this context, Dimmeler examines the necessary messenger substances , the development of damage to these cell structures and the possibilities of regenerating these processes. This basic research is primarily intended to provide a better understanding of the processes involved in arteriosclerosis and to identify treatment options for this. It also delivered initial results on stem cell therapy using progenitor cells from bone marrow for the treatment of heart attack patients . Current work also deals with the regulation of vascular growth and stem cells by small gene snippets, so-called microRNAs.
Awards
In addition to a number of grants and research funding, Stefanie Dimmeler was awarded the following prizes for her scientific work:
- 1991: Prize of the Stifterverband for German Science
- 1994: Fritz Külz Prize of the German Society for Pharmacology and Toxicology
- 1998: Research award from the German Heart Research Foundation
- 1999: Prize from the Herbert and Hedwig Eckelmann Foundation
- 2000: Fraenkel Prize of the German Society for Cardiology
- 2002: Alfried Krupp sponsorship award for young university teachers
- 2004: Forßmann Prize of the Ruhr University Bochum
- 2005: Gottfried Wilhelm Leibniz Prize of the German Research Foundation
- 2007: Ernst Jung Prize for Medicine 2007 , together with Andreas Zeiher
- 2008: Science4Life Venture Cup Prize
- 2010: Research Award from the GlaxoSmithKline Foundation
- 2014: Madrid Award for Stem Cell Therapy
- 2014 & 2015: Thomson Reuters "Highly Cited Researchers" (Top 1% of highly cited researchers)
- 2015: Louis B. Jaques Plenary Lecture, International Society of Thrombosis and Haemostasis
- 2015: ERC Advanced Investigator Grant
- 2015: Thomas W. Smith Memorial Lecture at Scientific Sessions
- 2016: Michael Oliver Memorial Lecture of the British Atherosclerosis Society
- 2016: Paul Dudley White Lecture at the Scientific Sessions of the AHA
- 2017: Willi Pitzer Prize, Bad Nauheim
- 2018: Selby Traveling Fellowship of the Australian Academy of Science
Publications
- Stem cell therapy in cardiology. Stand and prospects . Edited together with Andreas Zeiher. Uni-Med, Bremen 2004 ISBN 978-3-89599-800-3
More information on publications: www.cardiovascular-regeneration.com and www.ncbi.nlm.nih.gov/pubmed
Web links
- Portrait at the DFG ( Memento from September 29, 2007 in the Internet Archive )
- Literature by and about Stefanie Dimmeler in the catalog of the German National Library
- Institute of Cardiovascular Regeneration (Engl.)
- Stefanie Dimmeler in the database of renowned scientists AcademiaNet
Individual evidence
- ↑ Member entry by Stefanie Dimmeler (with picture) at the German Academy of Natural Scientists Leopoldina , accessed on September 15, 2017.
- ^ RheinMain: DZHK. Retrieved September 17, 2019 .
- ↑ BMBF Internet editorial office: German Centers for Health Research - BMBF. Retrieved September 17, 2019 .
- ↑ DFG - EXS 2026: Cardio-Pulmonary Institute (CPI). Retrieved on September 17, 2019 (German).
| personal data | |
|---|---|
| SURNAME | Dimmeler, Stefanie |
| BRIEF DESCRIPTION | German biologist and biochemist |
| DATE OF BIRTH | July 18, 1967 |
| PLACE OF BIRTH | Ravensburg |