3-aminopropyltriethoxysilane

Structural formula
General
Surname	3-aminopropyltriethoxysilane
other names	APTES
Molecular formula	C 9 H 23 NO 3 Si
Brief description	colorless liquid with an amine-like odor
External identifiers / databases
CAS number 919-30-2 EC number 213-048-4 ECHA InfoCard 100,011,863 PubChem 13521 ChemSpider 12933 Wikidata Q4542878
properties
Molar mass	221.37 g mol −1
Physical state	liquid
density	0.95 g cm −3
Melting point	<-70 ° C
boiling point	217 ° C
Vapor pressure	11 hPa (20 ° C)
solubility	decomposes in water
Refractive index	1.421 (20 ° C)
safety instructions
GHS hazard labeling from  Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary danger H and P phrases H: 302-314-317 P: 280-301 + 330 + 331-302 + 352-305 + 351 + 338-308 + 310
Toxicological data	1780 mg kg −1 ( LD 50 ,  rat ,  oral ) 3800 mg kg −1 ( LD 50 ,  rabbit ,  transdermal )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

3-aminopropyltriethoxysilane is a chemical compound from the group of organosilicon compounds .

Extraction and presentation

3-aminopropyltriethoxysilane can be obtained by catalyzed hydrogenation of the corresponding nitrile ( 2-cyanoethyltriethoxysilane ).

properties

3-aminopropyltriethoxysilane is a flammable, hardly inflammable, colorless liquid with an amine-like odor that decomposes in water. Its aqueous solution has an alkaline reaction. The half-life in water is 8.4 hours at pH 7 and 24.7 ° C. In the basic and acidic range, the compound decomposes quickly.

use

3-aminopropyltriethoxysilane is used in a variety of ways and includes various applications as an adhesion promoter in glass fibers , adhesives and sealants, casting resins and in the pretreatment of coatings, as well as for the production of dental and orthopedic materials. The compound is also used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.

safety instructions

The vapors of 3-aminopropyltriethoxysilane can form an explosive mixture with air ( flash point 93 ° C, ignition temperature 300 ° C).

Individual evidence

1. ↑ ^{a b c d e f g h i j k l m} Entry on 3-aminopropyltriethoxysilane in the GESTIS substance database of the IFA , accessed on January 24, 2019(JavaScript required) .
2. ↑ Data sheet (3-aminopropyl) triethoxysilane, ≥98.0% from Sigma-Aldrich , accessed on January 24, 2019 ( PDF ).
3. ↑ Entry on 3-aminopropyltriethoxysilane in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on January 29, 2019. Manufacturers or distributors can expand the harmonized classification and labeling .
4. ↑ ^{a b} Entry on 3-aminopropyltriethoxysilane in the Hazardous Substances Data Bank , accessed on January 24, 2019.
5. ↑ OECD : Screening Information Dataset (SIDS) Initial Assessment Report (SIAR) for 1-Propylamine, 3- (triethoxysilyl) - , accessed on January 24, 2019.
6. ↑ Data sheet (3-aminopropyl) triethoxysilane, 98% from AlfaAesar, accessed on January 24, 2019 ( PDF )(JavaScript required) .