Arthur B. Pardee

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Arthur Beck Pardee (born July 13, 1921 in Chicago , Illinois - † February 24, 2019 ) was an American pharmacologist and biochemist who received the prestigious Rosenstiel Award in 1975 .

biography

After attending school, Pardee began studying at the University of California, Berkeley in 1942 and worked there as a researcher until 1961. In addition, he was a visiting researcher at the California Institute of Technology in 1943 and from 1947 to 1949 at the University of Wisconsin – Madison , before he also worked as a visiting researcher at the Pasteur Institute in Paris from 1957 to 1958 .

In 1961 he accepted a position as professor of biochemistry at Princeton University and was last from 1975 until his retirement in 1997 professor of pharmacology at Harvard Medical School .

After early research in the fields of redox reactions , tumor metabolome and antibody reactions, he dealt with how cells control their translation . He also discovered feedback controls in the synthesis of amino acids . In addition, his studies of deoxyribonucleic acid (DNA) led to the investigation of a number of specific inhibitors that regulate biochemical processes. Most recently, he investigated the effects of peptides including insulin-like growth factors from the beginning of the 1980s , and in 1984 the ubiquitin system.

For his achievements, he received the Pfizer Award in Enzyme Chemistry in 1960 and, in 1975, together with H. Edwin Umbarger, the Rosenstiel Award from Brandeis University . In 1963 he was elected to the American Academy of Arts and Sciences , 1968 to the National Academy of Sciences and in 2001 to the American Philosophical Society . From 1984 to 1985 he was President of the American Association for Cancer Research .

literature

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Individual evidence

  1. Arthur B. Pardee. National Academy of Sciences, accessed February 27, 2019 .
  2. ^ Member History: Arthur B. Pardee. American Philosophical Society, accessed November 28, 2018 (with biographical notes).