Clodinafop propargyl

Structural formula
General
Surname	Clodinafop propargyl
other names	Prop-2-ynyl- ( R ) -2- [4- (5-chloro-3-fluoro-2-pyridyloxy) phenoxy] propionate ( IUPAC ); 2-propynyl (2 R ) -2- [4 - [(5-chloro-3-fluoro-2-pyridinyl) oxy] phenoxy] propanoate;
Molecular formula	C 17 H 13 ClFNO 4
Brief description	colorless and odorless solid
External identifiers / databases
EC number	600-662-6
ECHA InfoCard	100.132.475
PubChem	92431
ChemSpider	83449
Wikidata	Q1102118
properties
Molar mass	349.74 g mol −1
Physical state	firmly
density	1.37 g cm −3
Melting point	59.6 ° C
boiling point	100.6 ° C at 0.082 Pa
Vapor pressure	3.19 × 10 −6 hPa (25 ° C)
solubility	soluble in most organic solvents such as acetone and toluene; practically insoluble in water (4.0 mg l −1 at 25 ° C);
safety instructions
H and P phrases	H: 302 + 332-317-373-410
	P: 273-280-301 + 312 + 330-302 + 352-304 + 340 + 312-314
Toxicological data	1829 mg kg −1 ( LD 50 , rat , oral ) ; > 2000 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Clodinafop-propargyl is a chemical compound from the aryloxyphenoxypropionate group . It is the propargyl - esters of clodinafop .

Extraction and presentation

Clodinafop-propargyl can be obtained by reacting 2-fluoro-4-chloropyridine with propynyl-2- (4-chlorophenoxy) propionate .

properties

Clodinafop-propargyl is a colorless and odorless solid. It hydrolyzes slowly under acidic conditions but rapidly under alkaline conditions. Photolysis occurs rapidly, producing an abundance of other chemical compounds, but not clodinafop (free acid). The compound decomposes from a temperature of 285 ° C.

use

Clodinafop-propargyl is used as a herbicide and is effective against grasses, but not against broad-leaved weeds. The effect is based on the inhibition of fatty acid synthesis and the inhibition of acetyl-coenzyme-A-carboxylase. It is often used with the herbicide safener Cloquintocet-mexyl .

Admission status

In Switzerland, plant protection products with clodinafop-propargyl as an active ingredient are approved, in Germany and Austria none.

Clodinafop was approved for use as a herbicide in the European Union effective February 1, 2007. In Germany pesticides with this active ingredient are on the market, in Austria and Switzerland, however, not.

Individual evidence

↑ ^a ^b ^c ^d Entry on clodinafop-propargyl in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .
↑ ^a ^b ^c ^d ^e ^f ^g Entry on Clodinafop-propargyl in the Hazardous Substances Data Bank , accessed on October 16, 2012.
↑ ^a ^b ^c ^d ^e ^f fao: Clodinafop (pdf; 168 kB)
↑ Entry on clodinafop-propargyl (ISO) in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Clodinafop-propargyl Suppliers: Clodinafop-propargyl - aryloxyphenoxy propionate - Clodinafop - Clodinafop-propargyl Suppliers
↑ Entry on Clodinafop-propargyl in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on August 1, 2013.
^ Bill Carlile: Pesticide Selectivity, Health and the Environment . Cambridge University Press, 2006, ISBN 0-521-81194-5 , pp. 52 ( limited preview in Google Book search).
^ Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on January 19, 2020.
↑ Directive 2006/39 / EC of the Commission of April 12, 2006 amending Directive 91/414 / EEC of the Council to include the active substances clodinafop, pirimicarb, rimsulfuron, tolclofos-methyl and triticonazole (PDF)
↑ General Directorate Health and Food Safety of the European Commission: Entry on Clodinafop in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on January 19, 2020.

[GESTIS-1] Entry on clodinafop-propargyl in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .

[HSDB-2] ↑ ^a ^b ^c ^d ^e ^f ^g Entry on Clodinafop-propargyl in the Hazardous Substances Data Bank , accessed on October 16, 2012.

[fao.org-3] ↑ ^a ^b ^c ^d ^e ^f fao: Clodinafop (pdf; 168 kB)

[CLP_100.132.475-4] Entry on clodinafop-propargyl (ISO) in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[Clodinafop-propargyl_Suppliers-5] Clodinafop-propargyl Suppliers: Clodinafop-propargyl - aryloxyphenoxy propionate - Clodinafop - Clodinafop-propargyl Suppliers

[herts.ac.uk-6] Entry on Clodinafop-propargyl in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on August 1, 2013.

[Bill_Carlile-7] Bill Carlile: Pesticide Selectivity, Health and the Environment . Cambridge University Press, 2006, ISBN 0-521-81194-5 , pp. 52 ( limited preview in Google Book search).

[PSM-Clodinafop-propargyl-8] Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on January 19, 2020.

[9] Directive 2006/39 / EC of the Commission of April 12, 2006 amending Directive 91/414 / EEC of the Council to include the active substances clodinafop, pirimicarb, rimsulfuron, tolclofos-methyl and triticonazole (PDF)

[PSM-Clodinafop-10] General Directorate Health and Food Safety of the European Commission: Entry on Clodinafop in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on January 19, 2020.