Cloxacillin
Structural formula | ||||||||||||||||||||||
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General | ||||||||||||||||||||||
Non-proprietary name | Cloxacillin | |||||||||||||||||||||
other names |
(2 S , 5 R , 6 R ) -6 - {[3- (2-chlorophenyl) -5-methyl-oxazole-4-carbonyl] amino} -3,3-dimethyl-7-oxo-4-thia- 1-azabicyclo [3.2.0] heptane-2-carboxylic acid ( IUPAC ) |
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Molecular formula | C 19 H 18 ClN 3 O 5 S | |||||||||||||||||||||
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Drug information | ||||||||||||||||||||||
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Drug class |
Isoxazolyl penicillin |
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properties | ||||||||||||||||||||||
Molar mass | 435.88 g · mol -1 | |||||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Cloxacillin is an antibiotic effective drug . The substance from the group of β-lactam antibiotics belongs to the penicillinase- resistant penicillins. Cloxacillin is mainly used today in veterinary medicine , in Germany there is no preparation for humans on the market.
The main areas of application indicated are infections with penicillin-resistant staphylococci , such as skin and soft tissue infections ( impetigo , cellulitis , pyomyositis ), endocarditis , septicemia , pneumonia , osteomyelitis and the like. a. The spectrum of activity corresponds to that of other isoxazolyl penicillins, which include oxacillin , dicloxacillin , flucloxacillin and methicillin . Cloxacillin differs from oxacillin in that it has an additional chlorine atom on the phenyl ring .
Cloxacillin is listed on the World Health Organization Essential Medicines List. It can be administered intravenously or orally .
Trade names
- Cloxapen , Tegopen , Orbenin (USA)
- Veterinary medicine: Aniclox , Cloxaben , Cloxamycin , Cloxin , Gelstamp , Klato clox , Mammin TS forte , Mastipent (Kombi), neoclox md (Kombi), Orbenin , Penivet , Vetoscon , Vetriclox , Wedeclox
Web links
- Entry on Cloxacillin at Vetpharm, accessed August 4, 2012.
Individual evidence
- ↑ a b Data sheet Cloxacillin sodium salt monohydrate from Sigma-Aldrich , accessed on February 5, 2018 ( PDF ).
- ↑ WHO Model List of Essential Medicines (PDF; 442 kB) ; Retrieved September 20, 2012.