Digitoxigenin

Structural formula
General
Surname	Digitoxigenin
other names	3 β , 14 β -dihydroxy-5 β- card-20 (22) -enolide
Molecular formula	C 23 H 34 O 4
Brief description	colorless, bitter-tasting prisms
External identifiers / databases
CAS number 143-62-4 EC number 205-603-4 ECHA InfoCard 100.005.095 PubChem 4369270 ChemSpider 3571902 Wikidata Q411469
properties
Molar mass	374.53 g · mol -1
Physical state	firmly
Melting point	253 ° C
solubility	soluble in many organic solvents slightly soluble in water and diethyl ether
safety instructions
GHS labeling of hazardous substances danger H and P phrases H: 300 P: 264-301 + 310
Toxicological data	26.17 mg kg −1 ( LD 50 ,  mouse ,  oral )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Digitoxigenin is a steroid from the hydrolysis of the cardiac glycoside digitoxin , which occurs in the foxglove , digitalis lanata .

Structure and properties

Structurally, digitoxigenin belongs to the group of cardenolides , a group of steroids with an active effect on the heart, which have an unsaturated γ-lactone as a common structural feature .

Individual evidence

1. ↑ ^{a b c d} Entry on digitalis glycosides. In: Römpp Online . Georg Thieme Verlag, accessed on December 28, 2014.
2. ↑ ^{a b} Entry on digitoxigenin in the GESTIS substance database of the IFA , accessed on February 8, 2017(JavaScript required) .
3. ^ Entry on digitoxigenin in the ChemIDplus database of the United States National Library of Medicine (NLM) .