Herbert Jackle

Herbert Jäckle (born July 6, 1949 in Konstanz ) is a German developmental biologist . From 2002 to 2014 he was Vice President of the Max Planck Society ; from 2015 to 2016 he was Managing Director of the Max Planck Institute for Biophysical Chemistry .

Life

Jäckle graduated from high school in 1969 at the Leibniz Gymnasium in Rottweil. Studying chemistry and biology at the Albert-Ludwigs-Universität Freiburg was followed by a doctorate at the university's biological faculty in 1977. He then worked there as an assistant at the Zoological Institute. From 1978 to 1980 he worked as a postdoctoral fellow at the University of Texas at Austin on the early development of insects.

In 1980 he returned to EMBL in Heidelberg, and in 1982 he became head of an independent junior research group at the Max Planck Institute for Virus Research . 1984 took place the habilitation at the University of Tübingen . In 1988 he was appointed professor and full professor for genetics at the Ludwig Maximilians University in Munich . Since January 1991 he has been a Scientific Member of the Max Planck Society and Director of the Department of "Molecular Developmental Biology" at the Max Planck Institute for Biophysical Chemistry in Goettingen. In 1993 he became honorary professor at the University of Göttingen. In June 2002 he was elected Vice President of the Max Planck Society by the Senate, and in June 2007 he was confirmed for a second term of office until 2014. Jäckle has been "retired" since 2017.

In 1985 Jäckle was accepted as a member of the European Molecular Biology Organization (EMBO), in 1990 in the Academia Europaea , in 1998 in the German Academy of Sciences Leopoldina and in 2000 in the Academy of Sciences in Göttingen .

Act

His research areas are molecular control mechanisms of the embryonic development of the fly Drosophila melanogaster and the energy homeostasis of organisms. Jäckle succeeded in identifying development control genes and molecular regulatory mechanisms in flies that are necessary for the formation of body segments. The control genes and their interactions, the basic molecular principles are also conserved in mammals. His projects on the regulation of energy homeostasis thus also open up access to an understanding of human obesity.

Awards

• 1985: Research Prize of the German Society for Cell Biology
• 1986: Gottfried Wilhelm Leibniz Prize
• 1990: Prize from the Feldberg Foundation
• 1992: Otto Bayer Prize
• 1992: Karl-Ritter-von-Frisch-Medal of the German Zoological Society
• 1999: Louis Jeantet Prize for Medicine, Geneva,
• 1999: Science Award: Research between Basics and Applications
• 1999: Gregor Mendel Medal from the German Academy of Sciences Leopoldina
• 1999: German Future Prize
• 2007: Honorary doctorate from the Weizmann Institute (Israel)
• 2010: Cross of Merit 1st Class of the Order of Merit of the Federal Republic of Germany
• 2013: Prize for International Scientific and Technical Cooperation ( Chinese Academy of Sciences )
• 2014: Luis Federico Leloir Prize of the Argentine Government
• 2014: State Prize of the People's Republic of China
• 2015: Honorary doctorate from the University of Basel (Switzerland)
• 2016: Honorary doctorate from the University of Konstanz
• 2019: Klaus Sander Prize of the Society for Developmental Biology

Publications (selection)

• M. Beller, C. Sztalryd, N. Southall, M. Bell, H. Jäckle, DS Auld, B. Oliver: COPI complex is a regulator of lipid homeostasis. In: PLoS Biology . Volume 6, 2008, pp. 2530-2549.
• S. Grönke, A. Mildner, S. Fellert, N. Tennagels, S. Petry, G. Müller, H. Jäckle, RP Kühnlein: Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila. In: Cell Metabolism . Volume 1, 2005, pp. 323-330.
• M. Hirosawa-Takamori, H.-R. Chung, H. Jäckle: Conserved selenoprotein synthesis is not critical for oxidative stress defense, the lifespan of Drosophila. In: EMBO reports. Volume 5, 2004, pp. 317-322.
• D. Niessing, S. Blanke, H. Jäckle: Bicoid associates with the 5'-cap-bound complex of caudal mRNA, represses translation. In: Genes Dev. Volume 16, 2002, pp. 2576-2582.
• F. Schöck, J. Reischl, E. Wimmer, H. Taubert, BA Purnell, H. Jäckle: Phenotypic suppression of empty spiracles is prevented by buttonhead. In: Nature . Volume 405, 2000, pp. 351-354.
• M. González-Gaitán, H. Jäckle: Role of Drosophila alpha-adaptin in presynaptic vesicle recycling. In: Cell . Volume 88, 1997, pp. 767-776.
• R. Rivera-Pomar, H. Jäckle: From gradients to stripes in Drosophila embryogenesis: filling in the gaps. In: Trends Genet. Volume 12, 1996, pp. 478-483.
• R. Rivera-Pomar, X. Lu, N. Perrimon, H. Taubert, H. Jäckle: Activation of posterior gap gene expression in the Drosophila blastoderm. In: Nature. Volume 376, 1995, pp. 253-256.
• G. Brönner, Q. Chu-LaGraff, CQ Doe, B. Cohen, D. Weigel, H. Taubert, H. Jäckle: Sp1 / egr-like zinc-finger protein required for endoderm specification, germ-layer formation in Drosophila. In: Nature. Volume 369, 1994, pp. 664-668.

Web links

• Literature by and about Herbert Jäckle in the catalog of the German National Library
• Homepage of the Jäckle department at the MPI for Biophysical Chemistry

Individual evidence

1. ↑ see page Organization of the MPI for Biophysical Chemistry , accessed on March 21, 2015.