Marjorie G. Horning

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Marjorie Janice Groothuis Horning (born August 23, 1917 in Detroit , Michigan , † June 11, 2020 in Houston , Texas ) was an American biochemist and pharmacologist .

Life

Marjorie Janice Groothuis studied at Goucher College in Baltimore , where she graduated with a Bachelor of Arts in 1938 . She then went to the University of Michigan , where she earned her master's degree in 1940 and her PhD in biochemistry in 1943. During her time as a doctoral student, she met her future husband, Evan C. Horning , who was also a chemist and taught at the University of Michigan; they married in 1942. Marjorie G. Horning stayed at the university until 1945, working as a research assistant in pediatrics at the University of Michigan Hospital .

Marjorie G. Horning went with her husband to Philadelphia at the University of Pennsylvania in 1945 and in 1951 to the National Heart Institute (now the National Heart, Lung, and Blood Institute ) of the National Institutes of Health (NIH) in Bethesda , Maryland . After ten years at the NIH, Marjorie G. Horning became Associate Professor at the College of Medicine at Baylor University in Texas in 1961 and Professor of Biochemistry at the University's Institute for Lipid Research in 1969 . She was also an Associate Professor of Biochemistry and Biophysics at the University of Houston .

Marjorie G. Horning researched the distribution and metabolism of drugs in the human body, with a particular focus on the transfer from the pregnant woman to the embryo or fetus . She showed that almost all drugs and drugs , or their breakdown products, reach the unborn child, and was instrumental in ensuring that warnings against the use of certain medications and the consumption of alcohol or nicotine during pregnancy from the 1980s onwards . In the 1950s, Marjorie and Evan Horning were also pioneers in the application of gas chromatography for biological questions and later also used mass spectrometry to identify the smallest quantities in analytical biochemistry.

Awards

literature

  • Leslie S. Ettre, Albert Zlatkis (Eds.): 75 Years of Chromatography: A Historical Dialogue. Elsevier Scientific, 1979, ISBN 0-444-41754-0 , pp. 141-150.
  • Tiffany K. Wayne: American Women of Science Since 1900 (Vol.1: Essays AH). ABC-Clio, 2011, ISBN 978-1-59884-158-9 , pp. 520 f.

Individual evidence

  1. ↑ Nekrolog (English)
  2. ↑ Norman Rabjohn: Evan C. Horning: June 6, 1916 - May 14, 1993. ( Memento of March 16, 2015 in the Internet Archive ) In: Organic Syntheses. Vol. 73, 1996, pp. XXV-XXVI.
  3. ^ Married Couples in Science at NIH. Office of NIH History, National Institutes of Health (NIH). Retrieved September 16, 2014.
  4. ↑ a b c d Tiffany K. Wayne: American Women of Science Since 1900 (Vol.1: Essays AH). ABC-Clio, 2011, p. 520 f.
  5. ↑ Leslie S. Ettre, Albert Zlatkis (Ed.): 75 Years of Chromatography: A Historical Dialogue. Elsevier Scientific, 1979, pp. 141-150.
  6. ^ Tswett Chromatography Medals. In: Anal. Chem. Vol. 59, No. 17, 1987, p. 1001A, doi : 10.1021 / ac00144a716 .
  7. ^ Frank H. Field and Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry. American Chemical Society (ACS). Retrieved September 16, 2014.
personal data
SURNAME Horning, Marjorie G.
ALTERNATIVE NAMES Horning, Marjorie Janice Groothuis (full name)
BRIEF DESCRIPTION American biochemist and pharmacologist
DATE OF BIRTH August 23, 1917
PLACE OF BIRTH Detroit , Michigan
DATE OF DEATH June 11, 2020
Place of death Houston , Texas