Max M. Burger

from Wikipedia, the free encyclopedia
Max Burger (2014)

Max Marcell Burger (born July 8, 1933 in Zurich ; † November 2, 2019 ) was a Swiss doctor and biochemist .

Life

Max M. Burger, professor emeritus for biochemistry , studied medicine at the University of Zurich and then biochemistry at Washington University , USA . From 1965 on, the double doctorate researcher, first as an assistant and associate professor and finally as a co-founder and full professor, in the Department of Biochemistry at Princeton University . In 1970 he was appointed to the newly founded Biozentrum of the University of Basel , where he was professor of biochemistry until 1987, five years of which as chairman of the institution. Between 1987 and 2000 he headed the Friedrich Miescher Institute for Biomedical Research in Basel . In 2005, Burger retired from the University of Basel. Burger was chairman of the biology and medicine division of the Swiss National Science Foundation , founder and head of the Novartis Science Board, and co-founder and member of the Senate of the Helmholtz Association of German Research Centers . He died on November 2, 2019 at the age of 86.

Act

Burger's research focused on the biochemistry of the cell surface in both tumor cells and marine sponges , specifically for the function of glycans and glycoproteins . He discovered that sialic acid elements in the cell membrane are able to make normal and malignant cells variable. He demonstrated that normal, healthy cells prevent cell contact, which does not work in cells infected with tumor viruses whose surface cell membrane is changed. His research on the cell surface of sea sponges revealed that multiglycanic cell-cell recognitions (Animal Recognition) were involved in the Cambrian Animal Explosion millions of years ago. In addition, Burger was able to explain that lectins inhibit growth on the cell surface, but cannot inhibit it on tumor cell surfaces.

Awards

Publications (selection)

  • Burger, MM: Isolation of a receptor complex for a tumor specific agglutinin from the neoplastic cell surface. Nature 219: 499-500 (1968). PMID 4299255
  • Pollack, RE & Burger, MM: Surface-specific characteristics of a contact-inhibited cell line containing the SV40 viral genome. Proc. Natl. Acad. Sci. USA 62, 1074-1076 (1969). PMID 4307873
  • Sheppard, JR, Levine, AJ & Burger, MM: Cell-surface changes after infection with oncogenic viruses: Requirement for synthesis of host DNA. Science 172: 1345-1346 (1971). PMID 4325520
  • Mannino, RJ & Burger, MM: Growth inhibition of animal cells by succinylated concanavalin A. Nature 256: 19-22 (1975). PMID 1169693
  • Fernandez-Busquets, X., Körnig, A., Bucior, I., Burger, MM & Anselmetti, D .: Self recognition and Ca 2+ -dependent Carbohydrate-carbohydrate Cell Adhesion Provide Clues to the Cambrian Explosion. Mol. Biol. Evol., 26 (11): 2551-2561 (2009). PMID 19648465

Web links

Individual evidence

  1. ↑ Emeriti. Biozentrum Basel, accessed on November 10, 2014
  2. ↑ Bloomberg Businessweek , accessed November 10, 2014
  3. ↑ Yves-Alain Barde to succeed Max Burger as Director of the Friedrich Miescher Institute , evaluategroup.com, accessed on November 10, 2014
  4. ↑ Honorary members of the SAMS ( Memento of the original from November 10, 2014 in the Internet Archive ) Info: The archive link has been inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. , samw.com, accessed November 10, 2014 @1@ 2Template: Webachiv / IABot / www.samw.ch
  5. ↑ Swiss National Science Foundation (SNSF) , accessed November 10, 2014
  6. ↑ Research area health ( memento of the original from November 10, 2014 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. helmholtz.de, accessed November 10, 2014 @1@ 2Template: Webachiv / IABot / www.helmholtz.de
  7. ^ Obituary for Prof. Max Burger. University of Basel, Biozentrum, November 12, 2019, accessed on November 13, 2019 .
  8. ↑ Cancer Research , aacrjournals.org, accessed November 10, 2014
  9. ↑ a b c CV Max M. Buger otto-naegeli-preis.ch, accessed on November 10, 2014
  10. ↑ Otto Naegeli Prize Winner 1975 , otto-naegeli-preis.ch, accessed November 10, 2014
  11. ↑ SAMS annual report ( Memento of the original of November 10, 2014 in the Internet Archive ) Info: The archive link has been inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. , samw.ch, accessed November 10, 2014 @1@ 2Template: Webachiv / IABot / www.samw.ch
  12. ^ Cancer Prize of the Swiss Cancer League. Prize winner since 1960. (PDF) In: krebsliga.ch. 2017, accessed February 3, 2018 .
  13. ^ Federal Cross of Merit to Prof. Max M. Burger. University of Basel , October 24, 2005, accessed on February 28, 2017 .
personal data
SURNAME Burger, Max M.
ALTERNATIVE NAMES Burger, Max Marcell
BRIEF DESCRIPTION Swiss doctor and biochemist
DATE OF BIRTH July 8, 1933
PLACE OF BIRTH Zurich
DATE OF DEATH 2nd November 2019