Sodium gluconate

Structural formula
General
Surname	Sodium gluconate
other names	E 576 ; Sodium D- gluconate; SODIUM GLUCONATE ( INCI ) ;
Molecular formula	C 6 H 11 NaO 7
Brief description	white, almost odorless solid
External identifiers / databases
EC number	208-407-7
ECHA InfoCard	100.007.644
PubChem	23672301
Wikidata	Q264552
properties
Molar mass	218.14 g mol −1
Physical state	firmly
density	0.8 g cm −3
Melting point	170-175 ° C
solubility	Easily soluble in water (590 g l −1 at 25 ° C); slightly soluble in ethanol ; practically insoluble in diethyl ether ;
safety instructions
GHS labeling of hazardous substances	no GHS pictograms
	no GHS pictograms
H and P phrases	H: no H-phrases
	P: no P-phrases
Toxicological data	> 2000 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Sodium gluconate is a chemical compound of sodium from the group of carboxylic acid salts and the sodium salt of gluconic acid .

Extraction and presentation

Sodium gluconate is produced technically by the oxidation of glucose or raw materials containing glucose (for example with caustic soda or sodium acetate ). The glucose can be oxidized chemically, electrolytically or biochemically (for example fermentation ).

properties

Sodium gluconate is a flammable, difficult to ignite, crystalline, white and almost odorless solid that is easily soluble in water. The compound decomposes at temperatures above around 200 ° C. The compound is resistant to hydrolysis, even for short periods at high temperatures and pH values.

use

Sodium gluconate is a good chelator at alkaline pH , with chelating performance better than EDTA , NTA and other chelators. It has a wide range of industrial uses including textile dyeing, water treatment, and as a cleaning agent for glass bottles. It is also used as a rust removal agent in metallurgy and as an additive in cement . The cleaning effect of sodium gluconate is based on the formation of metal ion complexes, which are stable in neutral and especially in alkaline environments. This is used for deoxidizing steel , copper and its alloys, for degreasing or etching aluminum and for dezincing workpieces. At 95 to 100 ° C, layers of paint and varnish are peeled off. It is used in foods to mask the bitter aftertaste of sweeteners, to improve the swellability and solubility of milk products and as an electrolyte regenerator.

The connection is considered harmless.

Individual evidence

↑ Entry on E 576: Sodium gluconate in the European database for food additives, accessed on June 28, 2020.
↑ Entry on SODIUM GLUCONATE in the CosIng database of the EU Commission, accessed on December 28, 2019.
↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on sodium gluconate in the GESTIS substance database of the IFA , accessed on January 9, 2019(JavaScript required) .
↑ ^a ^b ^c ^d data sheet Sodium D-gluconate, 97% from AlfaAesar, accessed on January 9, 2019 ( PDF )(JavaScript required) .
↑ Data sheet gluconic acid + sodium salt (PDF) from Merck , accessed on January 9, 2019.
↑ RB Bian, J. Shen: Synthesis of Sodium Gluconate by Bi Promoted Pd / C Catalyst. In: MATERIALS TRANSACTIONS. 48, 2007, p. 2252, doi : 10.2320 / matertrans.MRP2006634 .
↑ RH Blom, VF Pfeifer u. a .: SODIUM GLUCONATE PRODUCTION. FERMENTATION WITH ASPERGILLUS NIGER. In: Industrial & Engineering Chemistry. 44, 1952, p. 435, doi : 10.1021 / ie50506a061 .
↑ ^a ^b ^c Franz v. Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe: Hager's Handbook of Pharmaceutical Practice, Volume 5: Substances LZ . Springer-Verlag, 2013, ISBN 978-3-642-58388-9 , pp. 270 ( limited preview in Google Book search).
^ Gerhard Eisenbrand, Peter Schreier: RÖMPP Lexikon Lebensmittelchemie, 2nd edition, 2006 . Georg Thieme Verlag, 2014, ISBN 3-13-179282-5 , p. 447 ( limited preview in Google Book search).
↑ OECD : Screening Information Dataset (SIDS) Initial Assessment Report (SIAR) for Gluconic acid, monosodium salt , accessed on January 9, 2019.

[E-Nummer576-1] Entry on E 576: Sodium gluconate in the European database for food additives, accessed on June 28, 2020.

[CosIng-2] Entry on SODIUM GLUCONATE in the CosIng database of the EU Commission, accessed on December 28, 2019.

[GESTIS-3] ↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on sodium gluconate in the GESTIS substance database of the IFA , accessed on January 9, 2019(JavaScript required) .

[Alfa-4] ta sheet Sodium D-gluconate, 97% from AlfaAesar, accessed on January 9, 2019 ( PDF )(JavaScript required) .

[Merck-5] Data sheet gluconic acid + sodium salt (PDF) from Merck , accessed on January 9, 2019.

[DOI10.2320/matertrans.MRP2006634-6] RB Bian, J. Shen: Synthesis of Sodium Gluconate by Bi Promoted Pd / C Catalyst. In: MATERIALS TRANSACTIONS. 48, 2007, p. 2252, doi : 10.2320 / matertrans.MRP2006634 .

[DOI10.1021/ie50506a061-7] RH Blom, VF Pfeifer u. a .: SODIUM GLUCONATE PRODUCTION. FERMENTATION WITH ASPERGILLUS NIGER. In: Industrial & Engineering Chemistry. 44, 1952, p. 435, doi : 10.1021 / ie50506a061 .

[Franz_v._Bruchhausen,_Siegfried_Ebel,_Eberhard_Hackenthal,_Ulrike_Holzgrabe-8] Franz v. Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe: Hager's Handbook of Pharmaceutical Practice, Volume 5: Substances LZ . Springer-Verlag, 2013, ISBN 978-3-642-58388-9 , pp. 270 ( limited preview in Google Book search).

[Gerhard_Eisenbrand,_Peter_Schreier-9] Gerhard Eisenbrand, Peter Schreier: RÖMPP Lexikon Lebensmittelchemie, 2nd edition, 2006 . Georg Thieme Verlag, 2014, ISBN 3-13-179282-5 , p. 447 ( limited preview in Google Book search).

[SIDS-10] OECD : Screening Information Dataset (SIDS) Initial Assessment Report (SIAR) for Gluconic acid, monosodium salt , accessed on January 9, 2019.