Oliver Trapp

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Oliver Trapp (born June 9, 1973 in Göppingen ) is a German chemist. He has been researching and teaching since 2016 as a professor of organic chemistry at the Ludwig Maximilians University in Munich .

Life

Oliver Trapp grew up in Bad Boll ( Baden-Württemberg ) and attended the Mörike-Gymnasium in Göppingen. During his school days he took part in the Jugend forscht competition and was awarded the national prize in chemistry in 1992 for his work on the effects of a complexing agent on yeast and the prize of the German Research Foundation for interdisciplinary work. In 1992 he took first place at the 4th European Community Contest for Young Scientists.

From 1993 to 1998 he studied chemistry at the Eberhard Karls University in Tübingen . He wrote his diploma thesis on the “Synthesis of substituted 1,3-diphenylallenes, determination of interconversion barriers using stopped-flow multidimensional gas chromatography and simulation of elution profiles ” with Volker Schurig at the Institute for Organic Chemistry. In his doctoral thesis "Determination of the interconversion barriers of enantiomers , epimers and diastereomers by means of chromatographic methods and simulation of elution profiles in dynamic chromatography - theory and application", which he was a member of the graduate school "Chemistry in Interphases " and supported by a doctoral scholarship from the Fonds der Chemischen Industrie also produced in the working group of V. Schurig, he developed new techniques and algorithms for the fast and precise determination of enantiomerization barriers using enantioselective dynamic chromatography.

As a postdoc , Oliver Trapp did research in Richard N. Zare's group at Stanford University , funded by an Emmy Noether grant from the German Research Foundation. There he worked on the development of the Hadamard Transform Time-of-Flight mass spectrometry.

As an Emmy Noether junior research group leader , Oliver Trapp set up his own working group at the Max Planck Institute for Coal Research in Mülheim an der Ruhr . There he developed new methods for high throughput screening of new catalysts. In 2009 he completed his habilitation at the Ruhr University Bochum and received the Venia Legendi for chemistry.

In 2008 he accepted a call to a W3 professorship at the Ruprecht-Karls-Universität Heidelberg , where he taught and researched as a professor for organic chemistry until 2016. In 2015 and 2016, he was also the scientific coordinator of the Catalysis Research Laboratory (CaRLa) supported by BASF and the University of Heidelberg.

Oliver Trapp has been a Max Planck Research Fellow at the MPI for Astronomy and scientific coordinator of the Heidelberg Initiative for the Origins of Life (HIFOL) since 2015.

In 2016, he accepted an offer to succeed Herbert Mayr at the Department of Chemistry at the Ludwig Maximilians University in Munich and has been full professor for organic chemistry at the Faculty of Chemistry and Pharmacy since September 2016.

Oliver Trapp has been married to Gabriele Susanne Trapp (née Schoetz) since September 2001 and the couple has two children.

Research areas

In the course of his diploma and doctoral thesis, Oliver Trapp dealt with dynamic chromatography and determined interconversion barriers with the help of the ChromWin computer program he developed, among other things for the epimerization of chalcogran, the enantiomerization of oxazepam , thalidomide and chlorothalidone , the cis-trans isomerization of a dipeptide and the inversion barrier for stereogenic nitrogen atoms, e.g. B. Tröger's base or 1,3,4-oxadiazolidines. In 2006 he published his central work on "Unified Equation for Access to Rate Constants of First-Order-Reactions in Dynamic and On-Column Reaction Chromatography", with which the determination of rate constants and activation barriers of dynamic processes is possible on the basis of the elution profiles he also developed a software package.

In his independent research work, Oliver Trapp dealt with methods for high-throughput screening in chromatography through the integration of catalysis and separation in on-column reaction chromatography through multiplexing using the Hadamard transformation, which increases the duty cycle and improves the signal-to-noise ratio can be. Several samples of a multi-channel Multiplexinginjektor according to an n- bit - pseudo-random sequence in the chromatographic separation system injected (up to 3000 injections per hour). The entire chromatogram, which is recorded on the column after the individual analytes have been separated, represents a convolution of the overlapping, time-shifted individual chromatograms that can be obtained using an algorithm developed by Oliver Trapp . His work from this period moves at the interface between analytical chemistry and information technology and also included the investigation of the behavior of numerous stereodynamic molecular systems and reactions using gas and liquid chromatographic methods.

Oliver Trapp successfully applied the chromatographic methods he developed to the investigation of catalytic reactions. The stereochemistry of molecules can be seen as the overarching topic of his research projects . In a work that received a lot of attention in cooperation with scientific partners, he was able to directly demonstrate the absolute configuration of small molecules in the gas phase using Coulomb explosions . He and his group also developed new stereochemically flexible ligands that change their stereochemical properties through non- covalent interactions with chiral molecules in solution or under temperature control. By having the product of a catalytic reaction itself control the stereochemical properties of the catalyst, the enantioselective self-amplification of a product stereoisomer can be achieved. Oliver Trapp and his group at LMU Munich are investigating the importance of this aspect as well as other important reactions for the origin of life on earth in collaboration with partners from the interdisciplinary research cooperations OLIM (Origins of Life Initiative Munich) and HIFOL (Heidelberg Initiative for the Origins of Life).

Scheme of a self-amplifying enantioselective catalysis.

Honourings and prices

1992 National winner Jugend forscht
1992 Prize from the German Research Foundation (DFG) for an interdisciplinary research project
1992 First prize in the 4th European competition for young scientists
1993 Exchange grant from the European Union to participate in the 44th International Science and Engineering Fair
1999-2001 PhD scholarship from the Chemical Industry Fund (FCI)
2001 Attempto Prize from the Faculty of Chemistry, Pharmacy and Biochemistry at the University of Tübingen
2001 Procter & Gamble Innovation Award for the best dissertation at the Faculty of Chemistry at the University of Tübingen in 2001
2002 Emmy Noether Grant from the German Research Foundation (DFG)
2003 Prize of the Society of German Chemists (GDCh) in analytical chemistry
2005 Emmy Noether Junior Research Group Leader
2007 Thieme Journal Award
2007 Merck Research Grant Award
2008 Member of the Junge Kolleg of the North Rhine-Westphalian Academy of Sciences and Arts
2008 ADUC Prize from the Society of German Chemists for the best habilitation in 2008
2008 Heinz Maier Leibnitz Prize of the German Research Foundation
2008 2008 innovation award from the state of North Rhine-Westphalia
2009 Research award from Heidelberg University
2010 HTC-11 Award
2010 ERC Starting Independent Researcher Grant
2011 Capital Young Elite “4 times 40 under 40 year-olds”
2012 ERC Proof of Concept Grant
2015 Appointment as a Max Planck Research Fellow

Web links

Individual evidence

  1. ^ Trapp Research Group, LMU Munich , accessed on November 30, 2017.
  2. ↑ Jugend forscht, investigation of the effect of a complexing agent on yeast  ( page no longer available , search in web archives )  Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice. , accessed November 30, 2017.@1@ 2Template: Toter Link / www.jugend-forscht.de  
  3. ↑ Diploma and doctoral theses, Institute for Organic Chemistry Tübingen , accessed on November 30, 2017
  4. ^ Stanford University, Alumni of the Zare Lab , accessed November 30, 2017
  5. ↑ Trapp, New Techniques for High Throughput Screening of Catalysts, research report Max Planck Institute for Coal Research 2006 , accessed on November 30, 2017.
  6. ↑ Trapp, Heidelberg University ( Memento of the original from October 21, 2017 in the Internet Archive ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. , accessed November 30, 2017 @1@ 2Template: Webachiv / IABot / trapp.uni-hd.de
  7. ↑ CARLA, Catalytic Research Lab, University of Heidelberg, 2014, on the appointment of Trapp ( Memento of the original from December 1, 2017 in the Internet Archive ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. , accessed November 30, 2017 @1@ 2Template: Webachiv / IABot / www.carla-hd.de
  8. ↑ Prof. Dr. Oliver Trapp appointed MPG Fellow at the Max Planck Institute for Astronomy (MPIA) , Max Planck Institute for Astronomy, December 16, 2015, accessed on November 30, 2017
  9. ↑ Max Planck Institute for Astronomy, HIFOL , accessed on December 20, 2019
  10. ^ O. Trapp, V. Schurig, Comput. Chem. 2001, 25, 187-195.
  11. ↑ O. Trapp, V. Schurig, Chem. Eur. J. 2001, 7, 1495-1502.
  12. ↑ G. Schoetz, O. Trapp, V. Schurig, Anal. Chem. 2000, 72, 2758-2764.
  13. ↑ G. Schoetz, O. Trapp, V. Schurig, Enantiomer 2000, 5, 391-396.
  14. ↑ O. Trapp, G. Schoetz, V. Schurig, J. Pharm. Biomed. 2002, 27, 497-505.
  15. ↑ G. Schoetz, O. Trapp, V. Schurig, J. Capil. Electrophor. 1999, 6, 167-175.
  16. ↑ G. Schoetz, O. Trapp, V. Schurig, Electrophoresis 2001, 22, 2409-2415.
  17. ↑ O. Trapp, V. Schurig, J. Am. Chem. Soc. 2000, 122, 1424-1430.
  18. ↑ RG Kostyanovsky, GK Kadorkina, VR Kostyanovsky, V. Schurig, O. Trapp, Angew. Chem. 2000, 112, 3066-3069.
  19. ↑ O. Trapp, Anal. Chem. 2006, 78, 189-198.
  20. ↑ O. Trapp, Electrophoresis 2006, 27, 534-541.
  21. ↑ O. Trapp, Electrophoresis 2006, 27, 2999-3006.
  22. ↑ O. Trapp, SK Weber, S. Bauch, W. Hofstadt, Angew. Chem. 2007, 119, 7447-7451.
  23. ↑ O. Trapp, Angew. Chem. 2007, 119, 5706-5710.
  24. ↑ Heidelberg researchers form the absolute configuration of a chiral compound directly for the first time from the Heidelberg University page of November 28, 2013 , accessed on December 26, 2017.
  25. ↑ P. Herwig, K. Zawatzky, M. Grieser, O. Heber, B. Jordon-Thaden, C. Krantz, O. Novotny, R. Repnow, V. Schurig, D. Schwalm, Z. Vager, A. Wolf , O. Trapp, H. Kreckel, Science 2013, 342, 1084-1086.
  26. ↑ Chemists have for the first time developed a temperature-controlled catalyst that synthesizes both molecular mirror images of a compound. Page of the University of Heidelberg from March 12, 2015 , accessed on December 26, 2017.
  27. ↑ G. Storch, O. Trapp, Nature Chemistry 2017, 9, 179-187.
  28. ↑ Chiral Molecules: Quickly on one page, message from LMU dated December 1, 2016 , accessed on December 26, 2017.
  29. ↑ Origins of Life Initiative, LMU Munich , accessed on November 30, 2017
personal data
SURNAME Trapp, Oliver
BRIEF DESCRIPTION German chemist
DATE OF BIRTH June 9, 1973
PLACE OF BIRTH Goeppingen