Pencycuron

Structural formula
General
Surname	Pencycuron
other names	Monceren; 1- (4-chlorobenzyl) -1-cyclopentyl-3-phenylurea;
Molecular formula	C 19 H 21 ClN 2 O
Brief description	colorless crystals
External identifiers / databases
EC number	266-096-3
ECHA InfoCard	100.060.069
PubChem	91692
Wikidata	Q4989650
properties
Molar mass	328.84 g mol −1
Physical state	firmly
density	1.22 g cm −3
Melting point	132 ° C
boiling point	286 ° C, decomposition starts at 140 ° C
solubility	almost insoluble in water (0.0003 g l −1 at 20 ° C)
safety instructions
GHS hazard labeling from Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary Caution
H and P phrases	H: 410
	P: ?
Toxicological data	> 5000 mg kg −1 ( LD 50 , rat , oral ) ; > 2000 mg kg −1 ( LD 50 , rabbit , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Pencycuron is a chemical compound from the group of phenylureas .

Extraction and presentation

Pencycuron can be obtained by reacting 4-chlorobenzoyl chloride with cyclopentylamine and then with phenyl isocyanate .

use

Pencyuron has been used as a fungicide , especially against Rhizoctonia solani , since 1984 . Pencycuron works by inhibiting cell division .

Admission

After the approval application was withdrawn, the EU Commission decided in December 2008 not to include pencyuron in the list of active ingredients permitted for plant protection products. In response to a new application, pencyuron was finally added to this list for use as a fungicide in 2011. In Germany, Switzerland and Austria, plant protection products with the active ingredient pencycuron are approved.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g Entry on Pencycuron in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on October 31, 2013.
↑ Entry on Pencycuron in the GESTIS substance database of the IFA , accessed on January 10, 2017(JavaScript required) .
↑ Entry on pencycuron (ISO); 1 - [(4-chlorophenyl) methyl] -1-cyclopentyl-3-phenylurea in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on June 17, 2017. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 254 ( limited preview in Google Book search).
↑ Implementing Directive 2011/49 / EU of the Commission of April 18, 2011 (PDF) amending Council Directive 91/414 / EEC to include the active substance pencycuron and amending Commission Decision 2008/934 / EC.
↑ General Directorate Health and Food Safety of the European Commission: Entry on pencycuron in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; Retrieved February 19, 2016.

[ppdb-1] ↑ ^a ^b ^c ^d ^e ^f ^g Entry on Pencycuron in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on October 31, 2013.

[GESTIS-2] Entry on Pencycuron in the GESTIS substance database of the IFA , accessed on January 10, 2017(JavaScript required) .

[CLP_100.060.069-3] Entry on pencycuron (ISO); 1 - [(4-chlorophenyl) methyl] -1-cyclopentyl-3-phenylurea in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on June 17, 2017. Manufacturers or distributors can expand the harmonized classification and labeling .

[unger-4] Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 254 ( limited preview in Google Book search).

[5] Implementing Directive 2011/49 / EU of the Commission of April 18, 2011 (PDF) amending Council Directive 91/414 / EEC to include the active substance pencycuron and amending Commission Decision 2008/934 / EC.

[PSM-6] General Directorate Health and Food Safety of the European Commission: Entry on pencycuron in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; Retrieved February 19, 2016.