Roman Muschaweck

Roman Muschaweck (born  December 15, 1918 in Nuremberg ; †  May 2, 2007 ) was a German pharmacologist .

Live and act

Muschaweck attended elementary school in Hersbruck ( Franconia ) and humanistic grammar schools in Bamberg and Fürth . After graduating from high school in 1937, Muschaweck was drafted into the Reich Labor Service , then into the Air Force . In 1940 he began studying medicine at the Air Force student company in Würzburg , and in 1942 he moved to Heidelberg . In Fritz Eichholtz he received his doctorate with the thesis "The detection of astringents in gelatin" to Dr. med. After his license to practice medicine in December 1944, Muschaweck was returned to the military.

After the Second World War , Muschaweck initially worked in his own practice before finding a position as an assistant at Eichholtz at the Pharmacological Institute of Heidelberg University in 1946 . In 1948 he switched to industry and initially worked with Werner Keil at Rhein Chemie in Mannheim , and from 1952 at Rheinpreußen AG for mining and chemistry in Moers . In 1955, the pharmaceutical division of Rheinpreußen was taken over by Hoechst AG .

In 1959, Muschaweck was commissioned to test diuretics , in particular driving the laborious test of the substance Hoe 058 , which was later approved under the name furosemide (trade name Lasix). Other drugs that Muschaweck approved were polygelin (Haemaccel) and piretanid (Arelix). In 1974 he synthesized together with Robert Rippel the Articaine (Ultracain). Articain is the most widely used local anesthetic in continental Europe. In 2002, in recognition of his scientific achievements, he and Wulf Vater were awarded the Schmiedeberg plaque from the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT).

After his retirement, Muschaweck helped rebuild a pharmacological institute in Shanghai . Muschaweck was married and had six children.

literature

• Gerhard Vogel: Two distinguished pharmacologists turn 85. Roman Muschaweck In: BIOspektrum. 9 (6) / 2003. Spektrum Akademischer Verlag, p. 77, ISSN  0947-0867 (PDF file, approx. 91 kB)
• Gerhard Vogel: Obituary for Dr. med. Roman Muschaweck In: BIOspektrum. 13 (5 )/2007. Spektrum Akademischer Verlag, p. 547, ISSN  0947-0867 (PDF file, 222 kB)

Individual evidence

1. ^ Commemorative notice ( Memento of October 21, 2012 in the Internet Archive ) In: Hessisches Ärzteblatt. Edition 7/2007. Published by the State Medical Association of Hesse, p. 456, ISSN  0171-9661 (PDF file, approx. 526 kB)
2. ^ R. Muschaweck, R. Rippel: A new local anesthetic (carticaine) from the thiopene-series (author's transl.) In: Practical anesthesia, resuscitation and intensive therapy. Volume 9, Number 3, June 1974, pp. 135-146, PMID 4459901 .
3. ↑ Hans Christoph Niesel: Local anesthesia, regional anesthesia, regional pain therapy: 117 tables . Georg Thieme Verlag, 2010, ISBN 978-3-13-795403-3 , p. 598.