4-bromofluorobenzene

Structural formula
General
Surname	4-bromofluorobenzene
other names	1-bromo-4-fluorobenzene; 4-fluorobromobenzene; p-bromofluorobenzene;
Molecular formula	C 6 H 4 BrF
Brief description	colorless liquid with an aromatic odor
External identifiers / databases
EC number	207-300-2
ECHA InfoCard	100.006.638
PubChem	9993
ChemSpider	13875180
Wikidata	Q18049954
properties
Molar mass	175.00 g mol −1
Physical state	liquid
density	1.593 g cm −3
Melting point	-16 ° C
boiling point	150 ° C
Vapor pressure	4.99 hPa (25 ° C)
solubility	very sparingly soluble in water (0.14 g l −1 at 20 ° C)
Refractive index	1.527 (20 ° C)
safety instructions
H and P phrases	H: 226-332
	P: 210-261-370 + 378
Toxicological data	2700 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

4-Bromofluorobenzene is a chemical compound of bromine from the group of aromatic halogenated hydrocarbons .

Extraction and presentation

4-Bromofluorobenzene can be obtained by bromination of fluorobenzene in the presence of a catalyst .

properties

4-Bromofluorobenzene is a colorless liquid with an aromatic odor that is very sparingly soluble in water.

use

4-Bromofluorobenzene is used as an agrochemical intermediate, in organic syntheses and as a standard for gas chromatography - mass spectrometry for the determination of volatile organic compounds in various media. It is also used as an intermediate in the synthesis of atypical antipsychotic agents.

safety instructions

The vapors of 4-bromofluorobenzene can form an explosive mixture with air ( flash point 53 ° C).

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Entry on 4-bromofluorobenzene in the GESTIS substance database of the IFA , accessed on January 7, 2019(JavaScript required) .
↑ Data sheet 4-Bromofluorobenzene, analytical standard from Sigma-Aldrich , accessed on January 7, 2019 ( PDF ).
↑ ^a ^b U.S. Department of Health and Human Services: 4-Bromofluorobenzene CAS No. 460-00-4 Review of Toxicological Literature , accessed January 7, 2019
↑ Data sheet 1-Bromo-4-fluorobenzene, 99% from AlfaAesar, accessed on January 7, 2019 ( PDF )(JavaScript required) .

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Entry on 4-bromofluorobenzene in the GESTIS substance database of the IFA , accessed on January 7, 2019(JavaScript required) .

[Sigma-2] Data sheet 4-Bromofluorobenzene, analytical standard from Sigma-Aldrich , accessed on January 7, 2019 ( PDF ).

[ntp-3] U.S. Department of Health and Human Services: 4-Bromofluorobenzene CAS No. 460-00-4 Review of Toxicological Literature , accessed January 7, 2019

[Alfa-4] Data sheet 1-Bromo-4-fluorobenzene, 99% from AlfaAesar, accessed on January 7, 2019 ( PDF )(JavaScript required) .