Alexander Ellinger

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Alexander Ellinger (born  April 17, 1870 in Frankfurt am Main ; †  July 26, 1923 there ) was a German pharmacologist and physiologist of Jewish descent. He worked as a professor at the University of Königsberg from 1911 to 1914 and then at the University of Frankfurt until his death .

Life

Alexander Ellinger was born in Frankfurt am Main in 1870 and studied chemistry at the Universities of Berlin and Bonn from 1887 , which he completed with a doctorate in 1892 . During this time , August Wilhelm von Hofmann and August Friedrich Kekulé were among his academic teachers . He then studied medicine at the University of Munich . In 1897 he moved to the University of Königsberg , where he in 1898 also obtained the MD degree and a year later for Medicinal Chemistry and Pharmacology habilitated .

From 1911 he worked as a successor to Max Jaffé as a professor in Königsberg. In 1914 he moved to the newly founded University of Frankfurt in his hometown , where he was full professor of pharmacology until his death. The laboratories were housed in the Theodor Stern House together with those of the Chair of Vegetative Physiology, which was owned by Gustav Embden . Alexander Ellinger was also the first dean of the Frankfurt Medical Faculty.

He and his wife, a niece of Jaffé, had two daughters and two sons. He died in his hometown in 1923. Werner Lipschitz was appointed his successor in Frankfurt .

Scientific work

Alexander Ellinger's research focused on the chemical compound indole and substances derived from it, such as the amino acid tryptophan, as well as the exchange of water between tissues and blood , the formation of lymph and urine formation . During the First World War he made extensive attempts to treat combat gas poisoning .

Among other things, he discovered kynurenic acid as a metabolite of tryptophan and synthesized this amino acid for the first time with his colleague Claude Flamand. In 1917 he was awarded the title of Privy Medical Councilor. His last work was a review article on aromatic hydrocarbons in the Handbook of Experimental Pharmacology .

literature

  • Berthold Peter Anft:  Ellinger, Alexander. In: New German Biography (NDB). Volume 4, Duncker & Humblot, Berlin 1959, ISBN 3-428-00185-0 , p. 457 f. ( Digitized version ).
  • Udo Benzenhöfer: The University Medicine in Frankfurt am Main from 1914 to 2014. Kontur, Münster 2014, p. 53, ISBN 978-3-944998-01-5 .
  • Philipp Ellinger : Alexander Ellinger (1870-1923). In: Results of Physiology . Vol. 23, 1924, pp. 139-179 (Philipp Ellinger was a nephew of Alexander Ellinger).
  • Horst Grobecker, Gerd Geisslinger, Josef Pfeilschifter, Sebastian Harder: Center of Pharmacology, Medical Faculty of the Johann Wolfgang Goethe University Frankfurt am Main. In: Athineos Philippu (Ed.): History and work of the pharmacological, clinical-pharmacological and toxicological institutes in German-speaking countries. Berenkamp, ​​Innsbruck 2004, ISBN 3-85093-180-3 , pp. 204-210.

Web links

Individual evidence

  1. ↑ Udo Benzenhöfer : The University Medicine in Frankfurt am Main from 1914 to 2014. Kontur, Münster 2014, p. 53, ISBN 978-3-944998-01-5 .
  2. ↑ Alexander Ellinger: The emergence of tryptophan. In: Hoppe-Seylers Zeitschrift für Physiologische Chemie 43, 1904, pp. 325–337. Retrieved November 14, 2013.
  3. ^ J. Wang: Kynurenic Acid as a Ligand for Orphan G Protein-Coupled Receptor GPR35. In: Journal of Biological Chemistry. 281, 2006, pp. 22021-22028, doi : 10.1074 / jbc.M603503200 .
  4. ↑ Alexander Ellinger, Claude Flamand: About synthetically obtained tryptophan and some of its derivatives. In: Hoppe-Seylers Zeitschrift für Physiologische Chemie 55, 1907, pp. 8-24. Retrieved November 13, 2013.
  5. ↑ Charles Heidelberger : The synthesis of DL-tryptophan-β-C 14 , indole-3-acetic acid-α-C 14 , and DL-tryptophan-3-C 14 . in: Journal of Biological Chemistry 179, 1949, pp. 139-142. (PDF; 709 kB) Retrieved November 13, 2013.
  6. ↑ A. Ellinger: Aromatic hydrocarbons, phenols, aromatic acids, aromatic alcohols, aldehydes, ketones, quinones, nitro compounds. In: A.Heffter (Ed.): Handbook of experimental pharmacology . First volume, pp. 871-1048. Published by Julius Springer , Berlin, 1923.
personal data
SURNAME Ellinger, Alexander
BRIEF DESCRIPTION German pharmacologist
DATE OF BIRTH April 17, 1870
PLACE OF BIRTH Frankfurt am Main
DATE OF DEATH July 26, 1923
Place of death Frankfurt am Main